Detailed information NTG0928173

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: AB8O64_RS20440
• Genome accession: NZ_CP166299
• Coordinates: 4495990..4497114 (-)
• Length: 374 a.a.
• NCBI ID: WP_184739290.1
• Uniprot ID: A0A7W7LHE9
• Organism: Streptomyces sp. QH1-20
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4490990..4502114

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB8O64_RS20415 (AB8O64_20430)	-	4491172..4492956 (+)	1785	WP_370420496.1	sensor histidine kinase	-
AB8O64_RS20420 (AB8O64_20435)	-	4492953..4493615 (+)	663	WP_370420497.1	response regulator	-
AB8O64_RS20425 (AB8O64_20440)	-	4493700..4494179 (+)	480	WP_370420498.1	pyridoxamine 5'-phosphate oxidase family protein	-
AB8O64_RS20430 (AB8O64_20445)	-	4494233..4494820 (-)	588	WP_370420499.1	phosphatase PAP2 family protein	-
AB8O64_RS20435 (AB8O64_20450)	-	4495036..4495857 (+)	822	WP_370420500.1	hypothetical protein	-
AB8O64_RS20440 (AB8O64_20455)	disA	4495990..4497114 (-)	1125	WP_184739290.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
AB8O64_RS20445 (AB8O64_20460)	radA/sms	4497241..4498656 (-)	1416	WP_184739292.1	DNA repair protein RadA	Machinery gene
AB8O64_RS20450 (AB8O64_20465)	-	4498889..4500493 (+)	1605	WP_361934923.1	sigma-70 family RNA polymerase sigma factor	-
AB8O64_RS20455 (AB8O64_20470)	-	4500573..4501433 (-)	861	WP_370420502.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40114.94 Da
• Isoelectric Point: 5.0060

>NTDB_id=928173 AB8O64_RS20440 WP_184739290.1 4495990..4497114(-) (disA) [Streptomyces sp. QH1-20]
MAANDRASGPGKAGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLLVLGMDKTVESMCTGGFVLDVEFSATRLR
ELCKLDGALIVDKDITKIVRAGVQLVPDASIPTEETGTRHRTAQRVSIQCGYPVISVSQSMRLIALYVGGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLELVRRIATEIAEYVIELGTDGRLLSLQLEELIA
GVEPERDLVVRDYVPEPTAKRTRTVPEALSELDSLSHAELLELPIVARALGYSGSPETLDSAVSPRGYRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=928173 AB8O64_RS20440 WP_184739290.1 4495990..4497114(-) (disA) [Streptomyces sp. QH1-20]
GTGGCAGCCAACGACCGGGCATCGGGCCCCGGCAAGGCCGGGGGAAGCTCCGGTGCTGACGGTCTGATGCGCGCTTCGCT
GAGCGCCGTCGCGCCCGGCACGGCTCTTCGGGACGGCCTGGAGCGCATCCTTCGCGGCAATACCGGCGGGCTCCTCGTCC
TGGGCATGGACAAGACCGTCGAATCGATGTGTACGGGCGGATTCGTCCTCGATGTGGAGTTCTCCGCCACCCGGCTGCGC
GAGCTGTGCAAGCTGGACGGCGCGCTGATCGTCGACAAGGACATCACCAAGATCGTGCGGGCGGGCGTGCAGCTCGTCCC
CGATGCCTCGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACCGCGCAGCGCGTGTCCATCCAGTGCGGTTACCCCG
TCATCTCCGTCAGCCAGTCGATGCGGCTGATCGCGCTGTACGTGGGCGGTGAGCGCCGGGTCCTGGAGGAGTCGGGCGCG
ATCCTCTCCCGCGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTCCGTCTCGACGAGGTGGCCGGCACGCTCTC
CGCTCTGGAGATCGAGGATCTGGTCACCGTCCGCGATGTCACGGCGGTCTCCCAGCGGCTGGAGCTGGTCCGCCGTATCG
CCACGGAGATCGCGGAGTATGTGATCGAGCTGGGCACCGACGGCCGTCTGCTCTCGCTCCAGCTGGAGGAGTTGATCGCG
GGCGTCGAGCCGGAGCGCGACCTGGTCGTGCGGGACTACGTCCCGGAGCCGACCGCCAAGCGCACCCGCACGGTCCCGGA
GGCGCTCTCCGAGCTGGACTCCCTCAGCCACGCCGAGCTGCTCGAACTGCCCATCGTCGCGCGTGCCCTGGGTTACAGCG
GCTCCCCCGAGACGCTGGACTCCGCGGTCTCCCCGCGCGGCTACCGTCTGCTGGCCAAGGTGCCGCGGCTGCCCGGTGCG
ATCATCGACCGGCTCGTCGAGCACTTCGGCGGGCTCCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCCCGCGCCCGCTCGGTCCGCGAGGGGCTGTCCCGGCTCGCCGAGTCCTCGATCCTCGAGCGGTACG
TATAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: A0A7W7LHE9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.429	96.524	0.438