Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AB8K37_RS04575 Genome accession   NZ_CP166186
Coordinates   953345..954001 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CRE78     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 948345..959001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB8K37_RS04540 (AB8K37_04545) dcyD 949225..950211 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  AB8K37_RS04545 (AB8K37_04550) tcyL 950226..950894 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  AB8K37_RS04550 (AB8K37_04555) tcyN 950891..951643 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AB8K37_RS04555 (AB8K37_04560) sdiA 951873..952595 (+) 723 WP_106490481.1 transcriptional regulator SdiA -
  AB8K37_RS04560 (AB8K37_04565) yecF 952662..952886 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AB8K37_RS04565 (AB8K37_04570) yecU 952873..953049 (-) 177 WP_001326718.1 protein YecU -
  AB8K37_RS04570 (AB8K37_04575) - 953132..953203 (-) 72 Protein_888 transcriptional regulator -
  AB8K37_RS04575 (AB8K37_04580) letA 953345..954001 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AB8K37_RS04580 (AB8K37_04585) uvrC 953998..955830 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AB8K37_RS04585 (AB8K37_04590) pgsA 955887..956435 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB8K37_RS04610 (AB8K37_04615) - 958182..958544 (+) 363 Protein_893 DUF1524 domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=928063 AB8K37_RS04575 WP_000611335.1 953345..954001(+) (letA) [Escherichia coli strain CRE78]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=928063 AB8K37_RS04575 WP_000611335.1 953345..954001(+) (letA) [Escherichia coli strain CRE78]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486