Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AB9A07_RS05505 Genome accession   NZ_CP166018
Coordinates   1118502..1120283 (+) Length   593 a.a.
NCBI ID   WP_000390538.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GIMC7004:SaO-15 isolate GIMC7004:SaO-15     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1113502..1125283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB9A07_RS05485 (AB9A07_05495) polX 1113620..1115332 (+) 1713 WP_000161941.1 DNA polymerase/3'-5' exonuclease PolX -
  AB9A07_RS05490 (AB9A07_05500) mutS/mutS2 1115342..1117690 (+) 2349 WP_001249281.1 endonuclease MutS2 Machinery gene
  AB9A07_RS05495 (AB9A07_05505) trxA 1117863..1118177 (+) 315 WP_001018928.1 thioredoxin -
  AB9A07_RS05500 (AB9A07_05510) - 1118240..1118312 (-) 73 Protein_1080 hypothetical protein -
  AB9A07_RS05505 (AB9A07_05515) uvrC 1118502..1120283 (+) 1782 WP_000390538.1 excinuclease ABC subunit UvrC Machinery gene
  AB9A07_RS05510 (AB9A07_05520) - 1120607..1121221 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  AB9A07_RS05515 (AB9A07_05525) sdhA 1121273..1123039 (+) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  AB9A07_RS05520 (AB9A07_05530) sdhB 1123039..1123854 (+) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  AB9A07_RS05525 (AB9A07_05535) racE 1124095..1124895 (+) 801 WP_001836983.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68700.36 Da        Isoelectric Point: 9.7838

>NTDB_id=927987 AB9A07_RS05505 WP_000390538.1 1118502..1120283(+) (uvrC) [Staphylococcus aureus strain GIMC7004:SaO-15 isolate GIMC7004:SaO-15]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLQVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFIDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=927987 AB9A07_RS05505 WP_000390538.1 1118502..1120283(+) (uvrC) [Staphylococcus aureus strain GIMC7004:SaO-15 isolate GIMC7004:SaO-15]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGAGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGTTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATAAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAAAAATATCCTAGACTACAAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCATTAAATAATAAATTTGAATTAATATCACGTGATGAGTCAAGAACGATTAAAGCCATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTATCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAGGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTTGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565