Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AB3K28_RS09820 Genome accession   NZ_CP165737
Coordinates   2054628..2055284 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain PEC1013     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2049628..2060284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3K28_RS09790 dcyD 2050508..2051494 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  AB3K28_RS09795 tcyL 2051509..2052177 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AB3K28_RS09800 tcyN 2052174..2052926 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AB3K28_RS09805 sdiA 2053156..2053878 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  AB3K28_RS09810 yecF 2053945..2054169 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AB3K28_RS09815 yecU 2054156..2054332 (-) 177 WP_000590347.1 protein YecU -
  AB3K28_RS09820 letA 2054628..2055284 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AB3K28_RS09825 uvrC 2055281..2057113 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AB3K28_RS09830 pgsA 2057170..2057718 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB3K28_RS09850 yecA 2058368..2059033 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=927735 AB3K28_RS09820 WP_000611328.1 2054628..2055284(+) (letA) [Escherichia coli strain PEC1013]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=927735 AB3K28_RS09820 WP_000611328.1 2054628..2055284(+) (letA) [Escherichia coli strain PEC1013]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482