Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   QUR23_RS08225 Genome accession   NZ_CP165636
Coordinates   1697693..1698955 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain BSN11     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1692693..1703955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUR23_RS08200 (QUR23_08195) - 1692891..1693559 (-) 669 WP_000805950.1 uroporphyrinogen-III synthase -
  QUR23_RS08205 (QUR23_08200) hemC 1693581..1694507 (-) 927 WP_001230226.1 hydroxymethylbilane synthase -
  QUR23_RS08210 (QUR23_08205) ccsA 1694549..1695364 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  QUR23_RS08215 (QUR23_08210) hemA 1695386..1696732 (-) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  QUR23_RS08220 (QUR23_08215) yihA 1696949..1697539 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  QUR23_RS08225 (QUR23_08220) clpX 1697693..1698955 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  QUR23_RS08230 (QUR23_08225) tig 1699106..1700407 (-) 1302 WP_000127573.1 trigger factor -
  QUR23_RS08235 (QUR23_08230) - 1700455..1700565 (-) 111 WP_001790560.1 hypothetical protein -
  QUR23_RS08240 (QUR23_08235) - 1700570..1701499 (-) 930 WP_001280022.1 hypothetical protein -
  QUR23_RS08245 (QUR23_08240) - 1701518..1702126 (-) 609 WP_000032656.1 NUDIX domain-containing protein -
  QUR23_RS08250 (QUR23_08245) rplT 1702268..1702624 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  QUR23_RS08255 (QUR23_08250) rpmI 1702671..1702871 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  QUR23_RS08260 (QUR23_08255) infC 1702900..1703427 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=927240 QUR23_RS08225 WP_000472293.1 1697693..1698955(-) (clpX) [Staphylococcus aureus strain BSN11]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=927240 QUR23_RS08225 WP_000472293.1 1697693..1698955(-) (clpX) [Staphylococcus aureus strain BSN11]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACCTTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGAGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531