Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   VP459_RS04790 Genome accession   NZ_CP142600
Coordinates   1001074..1001643 (-) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain M19060305     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 996074..1006643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VP459_RS04750 (VP459_04745) - 996548..997156 (-) 609 WP_000020302.1 class I SAM-dependent methyltransferase -
  VP459_RS04755 (VP459_04750) rplL 997331..997699 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  VP459_RS04760 (VP459_04755) rplJ 997742..998242 (-) 501 WP_001273087.1 50S ribosomal protein L10 -
  VP459_RS04765 (VP459_04760) rplA 998514..999206 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  VP459_RS04770 (VP459_04765) rplK 999414..999836 (-) 423 WP_001085795.1 50S ribosomal protein L11 -
  VP459_RS04775 (VP459_04770) nusG 1000017..1000565 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  VP459_RS04780 (VP459_04775) secE 1000578..1000760 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  VP459_RS04785 (VP459_04780) rpmG 1000816..1000959 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  VP459_RS04790 (VP459_04785) sigH 1001074..1001643 (-) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  VP459_RS04795 (VP459_04790) - 1001724..1002248 (-) 525 WP_000664732.1 NYN domain-containing protein -
  VP459_RS04800 (VP459_04795) rlmB 1002248..1002994 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  VP459_RS04805 (VP459_04800) - 1003002..1003406 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  VP459_RS04810 (VP459_04805) cysS 1003399..1004799 (-) 1401 WP_000631963.1 cysteine--tRNA ligase -
  VP459_RS04815 (VP459_04810) cysE 1004783..1005430 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=926137 VP459_RS04790 WP_000872873.1 1001074..1001643(-) (sigH) [Staphylococcus aureus strain M19060305]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=926137 VP459_RS04790 WP_000872873.1 1001074..1001643(-) (sigH) [Staphylococcus aureus strain M19060305]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984