Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AB5J50_RS08420 Genome accession   NZ_CP163440
Coordinates   1770487..1771155 (+) Length   222 a.a.
NCBI ID   WP_327427044.1    Uniprot ID   A0ABW2VQK5
Organism   Streptomyces sp. R35     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1765487..1776155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB5J50_RS08395 (AB5J50_08395) - 1766626..1766979 (+) 354 WP_369265334.1 mismatch-specific DNA-glycosylase -
  AB5J50_RS08400 (AB5J50_08400) - 1766981..1767424 (-) 444 WP_369256383.1 hypothetical protein -
  AB5J50_RS08405 (AB5J50_08405) - 1767534..1768259 (-) 726 WP_369256385.1 ABC transporter permease subunit -
  AB5J50_RS08410 (AB5J50_08410) - 1768262..1769197 (-) 936 WP_327427042.1 ABC transporter ATP-binding protein -
  AB5J50_RS08415 (AB5J50_08415) - 1769306..1770472 (+) 1167 WP_369256387.1 sensor histidine kinase -
  AB5J50_RS08420 (AB5J50_08420) vraR 1770487..1771155 (+) 669 WP_327427044.1 response regulator transcription factor Regulator
  AB5J50_RS08425 (AB5J50_08425) - 1771278..1772435 (+) 1158 WP_327427045.1 ROK family transcriptional regulator -
  AB5J50_RS08430 (AB5J50_08430) - 1772520..1773281 (-) 762 WP_369256389.1 GntR family transcriptional regulator -
  AB5J50_RS08435 (AB5J50_08435) - 1773574..1774458 (-) 885 WP_369256391.1 RNA polymerase sigma-70 factor -
  AB5J50_RS08440 (AB5J50_08440) - 1774572..1775225 (+) 654 WP_369256393.1 NADPH-dependent F420 reductase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23510.11 Da        Isoelectric Point: 4.7428

>NTDB_id=925319 AB5J50_RS08420 WP_327427044.1 1770487..1771155(+) (vraR) [Streptomyces sp. R35]
MPVTVLLVDDEPLVRAGLRAVLEAQPDITVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLLDGIEATRAVLRTVSDPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRQLAAEYGDGDGAGNPVARAAMERAALT
EREAEVLRLMARGLSNAEIAARLIVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=925319 AB5J50_RS08420 WP_327427044.1 1770487..1771155(+) (vraR) [Streptomyces sp. R35]
ATGCCGGTCACCGTTCTCCTCGTCGACGACGAACCCCTCGTACGCGCGGGTCTGCGCGCCGTCCTGGAGGCGCAGCCCGA
CATCACGGTCGTCGGGGAGGCGGCCGACGGTGCGGCGGTGATCCCCTTGGTACGGCAGCTGCGGCCCGACGTGGTCGCCA
TGGACGTACGCATGCCGCTCCTGGACGGCATCGAGGCCACGCGCGCGGTGCTGCGCACCGTGAGCGATCCGCCGAAGATC
CTCGTGGTGACGACGTTCGAGAACGACGAGTACGTCTACGAGGCGCTGCGGGCGGGTGCCGACGGTTTTCTGCTGAAGCG
GGCGCGGCCCGCCGAGATCGTGCACGCGGTGCGGCTGGTCGCCGAGGGCGAGTCGCTGCTGTTTCCCGCCTCCGTACGGC
AGTTGGCCGCCGAGTACGGGGACGGGGACGGCGCCGGGAATCCAGTGGCGCGGGCGGCCATGGAGCGGGCCGCGCTGACC
GAGCGGGAGGCGGAGGTGCTGCGGCTGATGGCCCGGGGGCTGTCGAACGCGGAGATCGCCGCGCGGCTGATCGTCGGGAC
CGAGACGGTGAAGTCCCACGTCAGCGCCGTACTGGCGAAGCTGGGTGCCCGGGATCGTACGCAGGCGGTCATCGCGGCGT
ACGAGTCGGGGTTCGTGGCGCCCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.271

99.55

0.401
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.365