Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   VKP39_RS01355 Genome accession   NZ_CP142353
Coordinates   252832..253902 (+) Length   356 a.a.
NCBI ID   WP_002992231.1    Uniprot ID   A0A5S4TWS5
Organism   Streptococcus pyogenes strain D641     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 247832..258902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP39_RS01340 (VKP39_01340) amiA 248360..250330 (+) 1971 WP_326623875.1 peptide ABC transporter substrate-binding protein Regulator
  VKP39_RS01345 (VKP39_01345) amiC 250395..251897 (+) 1503 WP_002992227.1 ABC transporter permease Regulator
  VKP39_RS01350 (VKP39_01350) amiD 251897..252823 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  VKP39_RS01355 (VKP39_01355) amiE 252832..253902 (+) 1071 WP_002992231.1 ABC transporter ATP-binding protein Regulator
  VKP39_RS01360 (VKP39_01360) amiF 253895..254818 (+) 924 WP_109828742.1 ABC transporter ATP-binding protein Regulator
  VKP39_RS08660 - 254856..254945 (-) 90 WP_109821088.1 IS3 family transposase -
  VKP39_RS01365 (VKP39_01365) - 254966..255211 (-) 246 WP_186789748.1 transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39680.74 Da        Isoelectric Point: 5.4774

>NTDB_id=925149 VKP39_RS01355 WP_002992231.1 252832..253902(+) (amiE) [Streptococcus pyogenes strain D641]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=925149 VKP39_RS01355 WP_002992231.1 252832..253902(+) (amiE) [Streptococcus pyogenes strain D641]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S4TWS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537