Detailed information NTG0925102

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: AB5J48_RS18395
• Genome accession: NZ_CP163433
• Coordinates: 4123035..4124159 (-)
• Length: 374 a.a.
• NCBI ID: WP_031020135.1
• Uniprot ID: A0ACC6UQE7
• Organism: Streptomyces sp. R17
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4118035..4129159

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB5J48_RS18370 (AB5J48_18370)	cseB	4118532..4119227 (-)	696	WP_006129595.1	two-component system response regulator CseB	-
AB5J48_RS18375 (AB5J48_18375)	-	4119388..4120038 (-)	651	WP_006129594.1	hypothetical protein	-
AB5J48_RS18380 (AB5J48_18380)	-	4120026..4120565 (-)	540	WP_006129593.1	SigE family RNA polymerase sigma factor	-
AB5J48_RS18385 (AB5J48_18385)	-	4120848..4121783 (-)	936	WP_006129592.1	A/G-specific adenine glycosylase	-
AB5J48_RS18390 (AB5J48_18390)	-	4122060..4122950 (+)	891	WP_078592159.1	hypothetical protein	-
AB5J48_RS18395 (AB5J48_18395)	disA	4123035..4124159 (-)	1125	WP_031020135.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
AB5J48_RS18400 (AB5J48_18400)	radA	4124229..4125641 (-)	1413	WP_006129589.1	DNA repair protein RadA	Machinery gene
AB5J48_RS18405 (AB5J48_18405)	-	4126353..4128155 (+)	1803	WP_006129588.1	sigma-70 family RNA polymerase sigma factor	-
AB5J48_RS18410 (AB5J48_18410)	-	4128217..4129107 (-)	891	WP_369151621.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40014.71 Da
• Isoelectric Point: 5.0029

>NTDB_id=925102 AB5J48_RS18395 WP_031020135.1 4123035..4124159(-) (disA) [Streptomyces sp. R17]
MAANDRAAAPGKSGGSAGSDGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGSDKTVEALCSGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALHELDALTHAELLELPTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=925102 AB5J48_RS18395 WP_031020135.1 4123035..4124159(-) (disA) [Streptomyces sp. R17]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTTCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCCGTGGCACCCGGTACCGCCCTGCGTGACGGCCTGGAGCGCGTGCTCCGCGGCAACACGGGCGGGCTCATCGTGC
TCGGCTCGGACAAGACCGTCGAGGCGCTGTGCAGCGGCGGCTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCCTCGGACCTGTCGAAGATCCTGCGGGCCGGCGTCCAGCTGGTCCC
GGACCCGACGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTGAGCAAGCAGGTCGGCTTCCCTG
TGGTCTCCGTCTCCCAGTCGATGCGCCTGATCGCCCTCTACGTCGACGGCCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCCAACCAGGCGCTCGCCACCCTGGAGCGCTACAAGCTCCGTCTCGACGAGGTCGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCCGCGGTCGCGCAGCGGCTGGAGATGGTGCGCCGCATCG
CCACCGAAATCGCCGAATACGTGGTCGAACTGGGCACCGACGGCCGTCTTCTCGCCCTCCAGCTCGACGAGTTGATCGCC
GGCGTGGAGCCGGAACGCGAACTGGTCGTACGGGACTACGTCCCCGAGCCGACCGCGAAGCGCTCCCGCACGGTCGACGA
GGCGCTGCACGAGCTGGACGCGCTCACCCACGCGGAGCTGCTGGAACTGCCGACGGTGGCGCGTGCGCTCGGCTACACCG
GCTCCCCGGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGCCTGCTGGCGAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGCCTGGTGGAGCACTTCGGCGGACTGCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGCCTCTCCCGCCTGGCGGAAAGCAGCATCCTCGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.821	92.513	0.433