Detailed information NTG0925102

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: VKP38_RS03225
• Genome accession: NZ_CP142352
• Coordinates: 621724..622761 (+)
• Length: 345 a.a.
• NCBI ID: WP_032464469.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 2907-97
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 616724..627761

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP38_RS03200 (VKP38_03200)	-	616988..618319 (+)	1332	WP_063629299.1	dipeptidase	-
VKP38_RS03205 (VKP38_03205)	arcC	618339..619289 (+)	951	WP_010922501.1	carbamate kinase	-
VKP38_RS03210 (VKP38_03210)	asnA	619602..620594 (+)	993	WP_326612144.1	aspartate--ammonia ligase	-
VKP38_RS03215 (VKP38_03215)	rsmD	620717..621256 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
VKP38_RS03220 (VKP38_03220)	coaD	621246..621737 (+)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
VKP38_RS03225 (VKP38_03225)	sepM	621724..622761 (+)	1038	WP_032464469.1	SepM family pheromone-processing serine protease	Regulator
VKP38_RS03230 (VKP38_03230)	-	623166..624143 (+)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
VKP38_RS03235 (VKP38_03235)	-	624591..625211 (+)	621	WP_032464468.1	YutD family protein	-
VKP38_RS03240 (VKP38_03240)	rlmN	625215..626294 (+)	1080	WP_136097751.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
VKP38_RS03245 (VKP38_03245)	-	626376..627002 (-)	627	WP_002983834.1	prepilin peptidase	-
VKP38_RS03250 (VKP38_03250)	-	627230..627757 (+)	528	WP_002983837.1	Dps family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.17 Da
• Isoelectric Point: 9.5788

>NTDB_id=925102 VKP38_RS03225 WP_032464469.1 621724..622761(+) (sepM) [Streptococcus pyogenes strain 2907-97]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGN
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=925102 VKP38_RS03225 WP_032464469.1 621724..622761(+) (sepM) [Streptococcus pyogenes strain 2907-97]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAC
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69