Detailed information NTG0925103

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: VKP38_RS03345
• Genome accession: NZ_CP142352
• Coordinates: 646172..648454 (-)
• Length: 760 a.a.
• NCBI ID: WP_136097749.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 2907-97
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 641172..653454

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP38_RS03330 (VKP38_03330)	ileS	642170..644971 (+)	2802	WP_136097750.1	isoleucine--tRNA ligase	-
VKP38_RS03335 (VKP38_03335)	-	645236..645538 (-)	303	WP_002983878.1	DUF1827 family protein	-
VKP38_RS03340 (VKP38_03340)	-	645589..646044 (-)	456	WP_002989103.1	NUDIX hydrolase	-
VKP38_RS03345 (VKP38_03345)	clpE	646172..648454 (-)	2283	WP_136097749.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VKP38_RS03350 (VKP38_03350)	-	648752..648982 (+)	231	WP_002983885.1	YkuJ family protein	-
VKP38_RS03355 (VKP38_03355)	-	649109..649795 (+)	687	WP_032464463.1	amino acid ABC transporter permease	-
VKP38_RS03360 (VKP38_03360)	-	649795..650529 (+)	735	WP_002989107.1	amino acid ABC transporter ATP-binding protein	-
VKP38_RS03365 (VKP38_03365)	-	650678..652087 (+)	1410	WP_002993337.1	cryptochrome/photolyase family protein	-
VKP38_RS03370 (VKP38_03370)	-	652311..652664 (+)	354	WP_227868645.1	transposase	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 84674.87 Da
• Isoelectric Point: 5.0552

>NTDB_id=925103 VKP38_RS03345 WP_136097749.1 646172..648454(-) (clpE) [Streptococcus pyogenes strain 2907-97]
MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSILNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRYGGNYNGQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRAEDYERAAYFRDQ
ITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKQLRALMTNSENITIKAVKEGDSFLNEESLD

Nucleotide

• Length: 2283 bp

>NTDB_id=925103 VKP38_RS03345 WP_136097749.1 646172..648454(-) (clpE) [Streptococcus pyogenes strain 2907-97]
ATGCTGTGTCAAAATTGTAATTTAAACGAATCTACTATTCATCTTTATACAAGTGTTAATGGAAAACAAAGACAGGTTGA
TCTCTGTCAAAATTGTTATCAAATCATGAAATCCGATCCTGCCAATTCTATTTTAAATGGCCTAACCCCAGGATATAGAG
CACAAGATAGATCCACAAGTCCTTTCTTTGATGACTTTTTTGGTGATTTGAATAATTTTAGAGCTTTTGGTAATCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGCGGAGGACGCTATGGTGGTAACTACAACGGACAACGACCTGC
TCAGCCACAAACACCAAATCAGCAAGCAAAGGGCTTATTAGAAGAGTTTGGGATTAATGTCACAGATATTGCAAGAAATG
GTAATATTGATCCTGTTATTGGTCGTGACGAAGAGATTACACGCGTTATCGAGATCCTCAACCGCCGTACTAAAAATAAT
CCTGTGCTAATTGGTGAGCCTGGAGTTGGTAAAACTGCTGTTGTAGAAGGTTTGGCTCAAAAAATTATTGATGGTACTGT
TCCTCAAAAACTCCAAGGCAAGCAAGTGATTCGTCTTGATGTGGTTAGCCTCGTTCAGGGAACAGGTATCCGTGGTCAGT
TTGAAGAGCGCATGCAAAAATTAATGGAAGAAATTCGCAATCGCAAGGATGTGATTCTCTTTATTGATGAAATTCATGAG
ATTGTCGGTGCTGGTTCTGCAGGAGACGGCAATATGGATGCTGGTAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACATTAAATGAATACCGTATTATTGAAAAAGACGCTGCCTTAGAACGACGTATGCAACCCG
TTAAAGTTGATGAACCTTCTGTTGAGGAAACCATCACGATTTTAAAAGGTATCCAACCGAAATACGAAGACTATCATCAT
GTCAAATATAGCCCAGCCGCTATTGAAGCTGCCGCTCATTTATCTAACCGCTATATTCAAGACCGTTTTCTTCCTGATAA
GGCTATTGATCTTCTGGACGAAGCTGGTTCCAAAATGAATCTAACCCTCAACTTTGTTGATCCTAAAGAAATTGACAAAC
GTCTTATTGAAGCTGAGAATCTCAAGGCGCAAGCTACTCGAGCCGAAGACTATGAACGCGCAGCTTATTTCCGCGATCAA
ATTACAAAATACAAAGAAATGCAGGCTCAAAAAGTCGACGAGCAAGATATTCCCATCATTACTGAAAAAACCATTGAAGC
TATTGTAGAGCAAAAAACTAATATTCCAGTTGGGGACTTAAAAGAAAAGGAACAGTCTCAACTCGTAAACTTAGCCAATG
ATCTGAAAGCACACGTGATCGGGCAAGACGATGCTGTTGATAAAATCGCTAAGGCTATTCGTCGTAACCGTGTGGGATTA
GGAACTCCAAATCGCCCTATTGGTTCTTTCTTATTCGTTGGACCGACTGGGGTTGGTAAAACTGAATTGTCTAAACAACT
AGCCATTGAACTCTTTGGTTCGACAAACAATATGATTCGCTTTGACATGTCCGAATACATGGAAAAACACGCTGTCGCCA
AATTAGTCGGGGCTCCTCCAGGTTATGTCGGCTATGAAGAAGCTGGACAGCTAACCGAACAAGTTCGTCGCAATCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAAGCCCATCCTGACGTCATGCACATGTTCTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGAACAGTCAGCTTCAAGGACACCATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GCGAAGCTTCTGTCGGATTTGGTGCTGCTAGAGAAGGACGGACAAGTTCTGTCCTTGGTGAATTAAGCAACTTCTTCAGC
CCAGAGTTTATGAATCGTTTCGATGGTATTATTGAATTCAAAGCTTTATCTAAAGAGCATTTGCTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATGAGCGCTTAGGCTATAATGGGATTCATCTTGATGTGACACAAAAGGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGCGCTCGGCCGCTCCGTCGTACTATCCAAGATTATATAGAAGATGCCATTACA
GACTATTATTTAGAGCACCCAACTGAAAAACAGTTACGTGCACTGATGACAAACAGTGAAAATATCACGATTAAAGCTGT
TAAAGAGGGAGATTCTTTTCTTAACGAAGAGTCTCTCGATTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (656-729)

• AAA lid domain (AAA_lid_9) (300-396)

• AAA domain (Cdc48 subfamily) (AAA_2) (485-648)

• ATPase family associated with various cellular activities (AAA) (AAA) (162-281)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.626	98.421	0.833
clpE	Streptococcus pneumoniae Rx1	82.69	98.816	0.817
clpE	Streptococcus pneumoniae D39	82.69	98.816	0.817
clpE	Streptococcus pneumoniae R6	82.69	98.816	0.817
clpE	Streptococcus pneumoniae TIGR4	82.557	98.816	0.816
clpC	Lactococcus lactis subsp. cremoris KW2	75.296	100	0.754
clpC	Bacillus subtilis subsp. subtilis str. 168	51.593	86.711	0.447
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46	85.526	0.393
clpC	Streptococcus pneumoniae Rx1	46.825	82.895	0.388
clpC	Streptococcus pneumoniae D39	46.825	82.895	0.388
clpC	Streptococcus pneumoniae TIGR4	46.825	82.895	0.388
clpC	Streptococcus mutans UA159	47.573	81.316	0.387
clpC	Streptococcus thermophilus LMD-9	47.115	82.105	0.387
clpC	Streptococcus thermophilus LMG 18311	46.795	82.105	0.384