Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   Llc71_RS08285 Genome accession   NZ_AP025520
Coordinates   1668263..1669735 (-) Length   490 a.a.
NCBI ID   WP_046124519.1    Uniprot ID   -
Organism   Lactococcus cremoris strain 7-1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1663263..1674735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Llc71_RS08265 (Llc71_16570) murG 1663581..1664654 (-) 1074 WP_248536583.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  Llc71_RS08270 (Llc71_16580) murD 1664895..1666244 (-) 1350 WP_248536584.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  Llc71_RS08275 (Llc71_16590) - 1666413..1666754 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  Llc71_RS08280 (Llc71_16600) - 1666836..1668077 (-) 1242 WP_046124518.1 ammonium transporter -
  Llc71_RS08285 (Llc71_16610) covS 1668263..1669735 (-) 1473 WP_046124519.1 HAMP domain-containing histidine kinase Regulator
  Llc71_RS08290 (Llc71_16620) covR 1669748..1670440 (-) 693 WP_011676631.1 response regulator transcription factor Regulator
  Llc71_RS08295 (Llc71_16630) - 1670597..1671127 (-) 531 WP_046124520.1 DUF177 domain-containing protein -
  Llc71_RS08300 (Llc71_16640) - 1671260..1671505 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  Llc71_RS08305 (Llc71_16650) - 1671829..1672191 (-) 363 WP_046124521.1 TIGR02328 family protein -
  Llc71_RS08310 (Llc71_16660) - 1672427..1673338 (-) 912 WP_043735255.1 CHAP domain-containing protein -
  Llc71_RS08315 (Llc71_16670) - 1673431..1674267 (-) 837 WP_248536585.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55889.76 Da        Isoelectric Point: 4.7366

>NTDB_id=92508 Llc71_RS08285 WP_046124519.1 1668263..1669735(-) (covS) [Lactococcus cremoris strain 7-1]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNNMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=92508 Llc71_RS08285 WP_046124519.1 1668263..1669735(-) (covS) [Lactococcus cremoris strain 7-1]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACACGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGTGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATAATATGATGCTGAAAATGAAAGCATATCTTGAACAGCA
AAATCGGTTTGTCTCTGACGTTTCACATGAATTAAGGACTCCGCTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGGAAAAATGATCCAGAGGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945

Multiple sequence alignment