Detailed information NTG0092501

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: Llc71_RS02925
• Genome accession: NZ_AP025520
• Coordinates: 563819..566269 (+)
• Length: 816 a.a.
• NCBI ID: WP_248536868.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain 7-1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 558819..571269

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Llc71_RS02900 (Llc71_05480)	-	559583..560095 (+)	513	WP_011834623.1	adenine phosphoribosyltransferase	-
Llc71_RS02905 (Llc71_05490)	rpoE	560311..560874 (+)	564	WP_015082149.1	DNA-directed RNA polymerase subunit delta	-
Llc71_RS02910 (Llc71_05500)	mltG	561010..562650 (+)	1641	WP_046124950.1	endolytic transglycosylase MltG	-
Llc71_RS02915 (Llc71_05510)	greA	562711..563181 (+)	471	WP_011834626.1	transcription elongation factor GreA	-
Llc71_RS02920 (Llc71_05520)	-	563374..563829 (+)	456	WP_011834627.1	CtsR family transcriptional regulator	-
Llc71_RS02925 (Llc71_05530)	clpC	563819..566269 (+)	2451	WP_248536868.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
Llc71_RS02930 (Llc71_05540)	raiA	566404..566961 (+)	558	WP_046124948.1	ribosome-associated translation inhibitor RaiA	-
Llc71_RS02935 (Llc71_05550)	eno	567149..568450 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
Llc71_RS02940 (Llc71_05560)	-	568556..569227 (-)	672	WP_114693428.1	ABC transporter ATP-binding protein	-
Llc71_RS02945 (Llc71_05570)	-	569229..570302 (-)	1074	WP_248536869.1	ABC transporter permease	-
Llc71_RS02950 (Llc71_05580)	-	570314..570883 (-)	570	WP_011834636.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90364.75 Da
• Isoelectric Point: 6.6284

>NTDB_id=92501 Llc71_RS02925 WP_248536868.1 563819..566269(+) (clpC) [Lactococcus cremoris strain 7-1]
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRVEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSSDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=92501 Llc71_RS02925 WP_248536868.1 563819..566269(+) (clpC) [Lactococcus cremoris strain 7-1]
ATGAAATTTGAAAATGTAAAATATACACCAACACTGGACCGAATTTTCGAAAAAGCAGCAGAATATGCCCACCAATATCA
ATACGGTACGATTGAAAGTGCTCATTTATTGGCAGCAATGGCTACTACTTCAGGCTCAATTGCTTACAGTATTCTTGCTG
GAATGAATGTTGATTCTTCAGACTTACTGATTGATTTGGAAGATTTATCTAGCCATGTCAAAGTGAAACGTTCTGAATTA
CGTTTCTCTCCTCGCGTAGAAGAAGTGGTTACTGTAGCTAGCTTTTTGGCAGTTCATAATAATGCAGAAGCAGTAGGAAC
AGAGCATTTGCTTTATGCATTACTTCAAGTCGAAGATGGTTTTGGTCTTCAACTTTTGAAGTTACAAAAAATCAACATTG
TTTCTTTGCGAAAAGAAATTGAAAAAAGAACAGGACTTAAAGTTCCAGAAAACAAAAAAGCTGTAACACCAATGTCCAAA
CGTAAGATGGCAAAAGGGGTAGCAGAGAATTCAAGTACACCAACTTTGGATTCAGTTTCTTCAGATTTAACTGAAGCTGC
TCGTTCAGGAAAGCTTGACCCAATGATTGGTCGGGAAGCAGAAGTTGACCGTTTGATTCATATTCTTAGTCGTAGAACAA
AAAACAACCCTGTTTTAGTTGGTGAACCTGGTGTTGGTAAATCAGCAATAATCGAGGGATTGGCTCAAAGAATTGTCAAC
GGCCAAGTACCTATCGGTTTGATGAATAGCCGGATTATGGCCCTAAATATGGCAACTGTTGTTGCTGGTACAAAATTTAG
AGGTGAATTTGAAGACCGCTTGACAGCAATTGTTGAAGAAGTAAGTGCTGACCCAGATGTCATCATTTTCATTGATGAAT
TGCATACAATTATTGGTGCTGGCGGGGGCATGGACTCGGTCAATGATGCAGCAAATATTTTAAAACCAGCCCTTGCACGT
GGTGATTTTCAAATGGTTGGGGCAACGACTTATCATGAATACCAAAAATACATTGAAAAAGATGAAGCGTTAGAACGTCG
TTTGGCAAGAATCAATGTTGATGAGCCAAGTTCAGATGAAGCCATTGCTATCCTACAAGGGTTACGTGAGAAATTTGAAG
ATTATCATCAAGTGAAATTTACTGACCAAGCGATTAAAAGCGCTGTGACACTTAGTGTTCGGTACATGACCAGTCGCAAA
TTGCCTGATAAAGCCATCGACTTGCTTGATGAAGCAGCGGCAGCAGTTAAAATTTCTGTTAAAAACCAAGAAACAAAACG
TCTTGAATTAGAGAAAGACTTAGTTAAAGCTCAAGAAGAGCTAGCGGAAGCTGTCATTAAACTTGATGTTAAAGCCTCTC
GCATCAAAGAAAAAGCTGTTGAAAAAATTTCTGACAAGATTTATAAATTCTCAATAAAAGAGGAAAAACGTCAAGAAGTT
ACTGACCAAGCTGTTATTGCTGTTGCCTCAACGCTGACAGGTGTTCCAATTACTCAAATGACTAAATCTGAAAGCGACCG
TTTGATTAATCTTGAAAAAGAATTGCACAAACGGGTCGTTGGTCAAGAAGAAGCAATTTCTGCGGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTGGCTGATAGTCGCCGTCCAATGGGTTCATTTATGTTTCTTGGACCAACTGGTGTTGGGAAA
ACTGAGTTAGCTAAGGCCTTGGCCGATAGTGTTTTTGGTAGCGAAGACAACATGATTCGAGTGGATATGAGTGAATTTAT
GGAAAAACACTCTACTTCACGATTGATTGGAGCACCTCCAGGATATGTCGGTTATGATGAAGGTGGTCAATTGACTGAAC
GTGTTCGTAATAAACCCTATTCTGTGGTTCTTTTAGATGAAGTTGAGAAAGCTCATCCTGACGTTTTCAATATCATGCTC
CAAATTTTAGACGATGGATTTGTGACAGATACAAAAGGCCGCAAAGTTGATTTTAGAAATACAATTATTATCATGACTTC
AAACTTGGGTGCAACGGCTCTTCGTGATGATAAAACAGTTGGTTTTGGTGCAAAAAATATCACGGCTGACTACTCAGCTA
TGCAATCAAGAATTTTGGAAGAACTTAAACGTCATTATCGTCCAGAGTTTCTCAATCGTATTGATGAAAACATTGTTTTC
CATTCATTGGAAAGTCAAGAAATTGAACAAATTGTTAAGATTATGAGCAAATCTTTGATTAAACGTTTGGCGGAACAAGA
TATTCATGTGAAACTTACGCCATCAGCAATAAAACTAATCGCTGAAGTAGGATTTGACCCAGAATATGGGGCACGTCCAT
TGCGTAAAGCACTCCAAAAAGAAGTTGAAGATCTTTTAAGTGAACAATTGCTCTCGGGTGAGATTAAAGCAGGAAATCAT
ATTTCCATTGGTGCTTCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• AAA lid domain (AAA_lid_9) (357-449)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	95.833	100	0.958
clpC	Streptococcus thermophilus LMD-9	51.023	100	0.52
clpC	Streptococcus thermophilus LMG 18311	50.903	100	0.518
clpC	Streptococcus pneumoniae Rx1	49.517	100	0.502
clpC	Streptococcus pneumoniae D39	49.517	100	0.502
clpC	Streptococcus pneumoniae TIGR4	49.396	100	0.501
clpC	Streptococcus mutans UA159	49.038	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	50.125	98.284	0.493
clpE	Streptococcus mutans UA159	46.923	79.657	0.374
clpC	Lactococcus lactis subsp. cremoris KW2	46.626	79.902	0.373
clpE	Streptococcus pneumoniae TIGR4	47.049	76.838	0.362
clpE	Streptococcus pneumoniae Rx1	47.049	76.838	0.362
clpE	Streptococcus pneumoniae D39	47.049	76.838	0.362
clpE	Streptococcus pneumoniae R6	47.049	76.838	0.362