Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AB5J58_RS12440 Genome accession   NZ_CP163431
Coordinates   2672097..2672720 (-) Length   207 a.a.
NCBI ID   WP_352113769.1    Uniprot ID   -
Organism   Streptomyces sp. R08     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2667097..2677720
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB5J58_RS12420 (AB5J58_12420) - 2667554..2668783 (-) 1230 WP_328832610.1 DUF349 domain-containing protein -
  AB5J58_RS12425 (AB5J58_12425) - 2668919..2669746 (-) 828 WP_369187497.1 peptidylprolyl isomerase -
  AB5J58_RS12430 (AB5J58_12430) - 2669926..2670645 (+) 720 WP_328832612.1 MBL fold metallo-hydrolase -
  AB5J58_RS12435 (AB5J58_12435) hisS 2670656..2671918 (+) 1263 WP_369187498.1 histidine--tRNA ligase -
  AB5J58_RS12440 (AB5J58_12440) vraR 2672097..2672720 (-) 624 WP_352113769.1 response regulator transcription factor Regulator
  AB5J58_RS12445 (AB5J58_12445) - 2672717..2673943 (-) 1227 WP_369187499.1 sensor histidine kinase -
  AB5J58_RS12450 (AB5J58_12450) - 2673940..2674791 (-) 852 WP_369187500.1 ABC transporter permease -
  AB5J58_RS12455 (AB5J58_12455) - 2674788..2675654 (-) 867 WP_369187501.1 ABC transporter ATP-binding protein -
  AB5J58_RS12460 (AB5J58_12460) - 2675797..2676453 (+) 657 WP_369187502.1 vitamin K epoxide reductase family protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 22160.66 Da        Isoelectric Point: 5.8606

>NTDB_id=924916 AB5J58_RS12440 WP_352113769.1 2672097..2672720(-) (vraR) [Streptomyces sp. R08]
MIRIILADDHPVVREGLRAMLSAEPDLDVVADASSGPQAEALAAELRPDIVLMDLRMPGGGGVDSIVRMSAAGLPCRVIV
LTTYETDRDILRAVEAGAAGYLLKDLPRGELADAVRAAARGETVLAPSVAARLVDQLRTRPERPRLSVREVAVLRLVAEG
CTNAEIGRRLYIGESTVKTHLLRVFGKLGVDDRTAAVTSAMRYGLLD

Nucleotide


Download         Length: 624 bp        

>NTDB_id=924916 AB5J58_RS12440 WP_352113769.1 2672097..2672720(-) (vraR) [Streptomyces sp. R08]
ATGATCCGGATCATCCTGGCCGACGACCATCCCGTCGTACGGGAGGGCCTGCGCGCCATGCTCAGTGCCGAGCCGGATCT
CGATGTCGTCGCCGACGCGTCCAGTGGGCCTCAGGCGGAGGCGCTGGCGGCTGAACTCCGGCCCGACATCGTGCTGATGG
ACCTGCGGATGCCGGGGGGTGGGGGTGTCGACTCCATCGTGCGGATGAGTGCGGCGGGGTTGCCCTGCCGCGTCATCGTC
CTCACGACGTACGAGACCGACCGGGACATTCTGCGGGCCGTGGAGGCGGGGGCGGCGGGTTATCTGCTGAAGGATCTGCC
TCGGGGGGAACTCGCCGACGCGGTACGGGCCGCCGCGCGTGGCGAGACCGTGTTGGCGCCTTCCGTCGCGGCGCGGCTGG
TCGACCAGTTGCGGACCAGGCCTGAGCGGCCTCGGTTGTCCGTGCGGGAGGTCGCGGTGTTGCGGTTGGTGGCGGAGGGG
TGCACCAACGCCGAGATCGGGCGGCGGTTGTACATCGGGGAGTCCACCGTGAAGACCCATCTGCTGCGGGTCTTCGGCAA
GTTGGGGGTGGATGACCGGACCGCGGCGGTGACGAGTGCGATGCGGTACGGGTTGCTGGACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-200)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.864

99.517

0.377
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.367