Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   AB5J58_RS00620 Genome accession   NZ_CP163431
Coordinates   126122..127180 (-) Length   352 a.a.
NCBI ID   WP_266776516.1    Uniprot ID   -
Organism   Streptomyces sp. R08     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 121122..132180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB5J58_RS00595 (AB5J58_00595) cseB 121404..122111 (-) 708 WP_328830754.1 two-component system response regulator CseB -
  AB5J58_RS00600 (AB5J58_00600) - 122257..122850 (-) 594 WP_329557648.1 hypothetical protein -
  AB5J58_RS00605 (AB5J58_00605) - 122934..123473 (-) 540 WP_019064956.1 SigE family RNA polymerase sigma factor -
  AB5J58_RS00610 (AB5J58_00610) - 123774..124727 (-) 954 WP_369186146.1 A/G-specific adenine glycosylase -
  AB5J58_RS00615 (AB5J58_00615) - 125223..126044 (+) 822 WP_369186147.1 hypothetical protein -
  AB5J58_RS00620 (AB5J58_00620) disA 126122..127180 (-) 1059 WP_266776516.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  AB5J58_RS00625 (AB5J58_00625) radA/sms 127318..128727 (-) 1410 WP_266769766.1 DNA repair protein RadA Machinery gene
  AB5J58_RS00630 (AB5J58_00630) - 128926..130617 (+) 1692 WP_369186148.1 hypothetical protein -
  AB5J58_RS00635 (AB5J58_00635) - 130621..131478 (-) 858 WP_328830758.1 hypothetical protein -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38033.68 Da        Isoelectric Point: 4.8345

>NTDB_id=924893 AB5J58_RS00620 WP_266776516.1 126122..127180(-) (disA) [Streptomyces sp. R08]
MRASLSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFILDVEFTATRLRELCKLDGGIVVSSDLSKILRAG
VQLVPDPNIPTEETGTRHRTADRVSKQVAFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVVQRLEMVRLIATEIAEYVVELGTDGRLLALQLEELIAGVEPERELVVRDYVPEPTAKRS
RTVDEALAELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASVDD
LQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=924893 AB5J58_RS00620 WP_266776516.1 126122..127180(-) (disA) [Streptomyces sp. R08]
ATGCGCGCCTCACTGAGCGCCGTGGCCCCCGGCACGGCGTTGCGCGACGGCCTGGAGCGCATCCTCCGCGGCAACACGGG
CGGCCTCATCGTGCTCGGTTCCGACAAGACCGTCGAAGCGATGTGCACGGGCGGCTTCATCCTGGACGTCGAGTTCACGG
CCACGCGCCTGCGCGAACTGTGCAAGCTCGACGGCGGCATCGTGGTGTCGTCCGACCTCTCCAAGATCCTCCGGGCGGGC
GTCCAGCTGGTCCCCGACCCGAACATCCCCACCGAGGAGACCGGCACCCGCCACCGCACGGCGGACCGCGTCAGCAAACA
GGTCGCCTTCCCGGTGGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCCCTCTACGTGGACGGCCAGCGACGCGTCCTGG
AGGACTCGGCGGCGATCCTGTCCCGCGCCAACCAGGCCCTGGCGACACTGGAGCGCTACAAGCTCCGCCTGGACGAGGTG
GCGGGAACGTTGTCAGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCCGCGGTGGTCCAGCGGCTGGAGAT
GGTCCGGCTGATCGCCACCGAAATCGCCGAGTACGTAGTGGAGTTGGGCACGGACGGCCGCCTGCTCGCCCTCCAGCTGG
AGGAGTTGATCGCGGGCGTGGAGCCGGAGCGCGAACTCGTCGTACGCGACTACGTCCCCGAGCCCACGGCCAAACGATCC
CGCACGGTGGACGAGGCACTCGCCGAACTCGACGCCCTCTCCCACGCGGAACTCCTCGAACTCCCCACCGTGGCCCGCGC
GTTGGGCTACACCGGCTCCCCCGAGGCCCTCGACTCGGCGGTCTCCCCCCGCGGCTTCCGCCTGCTGGCCAAGGTCCCGC
GCCTCCCCGGCGCGATCATCGACCGCCTGGTCGAGCACTTCGGCGGCCTGCAGAAACTCCTGGCGGCAAGCGTCGACGAC
CTGCAGACGGTAGACGGCGTGGGCGAAGCGCGAGCACGCAGCGTCCGAGAGGGCCTCTCCCGCCTGGCGGAATCCTCAAT
CCTCGAACGCTACGTCTGA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)

Helix-hairpin-helix motif (HHH_2)

(302-337)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.665

98.295

0.449