Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AB4O71_RS09370 Genome accession   NZ_CP163122
Coordinates   1969454..1970110 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain W21 isolate China:Kunming     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1964454..1975110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4O71_RS09325 (AB4O71_09325) dcyD 1964556..1965542 (+) 987 WP_001565616.1 D-cysteine desulfhydrase -
  AB4O71_RS09330 (AB4O71_09330) tcyL 1965557..1966225 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AB4O71_RS09335 (AB4O71_09335) tcyN 1966222..1966974 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AB4O71_RS09340 (AB4O71_09340) sdiA 1967204..1967854 (+) 651 Protein_1822 transcriptional regulator SdiA -
  AB4O71_RS09350 (AB4O71_09350) - 1968593..1968703 (+) 111 Protein_1824 transcriptional regulator SdiA -
  AB4O71_RS09355 (AB4O71_09355) yecF 1968771..1968995 (-) 225 WP_000106473.1 DUF2594 family protein YecF -
  AB4O71_RS09360 (AB4O71_09360) yecU 1968982..1969158 (-) 177 WP_000590344.1 protein YecU -
  AB4O71_RS09365 (AB4O71_09365) - 1969196..1969312 (-) 117 WP_001302039.1 hypothetical protein -
  AB4O71_RS09370 (AB4O71_09370) letA 1969454..1970110 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AB4O71_RS09375 (AB4O71_09375) uvrC 1970107..1971939 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AB4O71_RS09380 (AB4O71_09380) pgsA 1971996..1972544 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB4O71_RS09400 (AB4O71_09400) yecA 1973194..1973859 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=924618 AB4O71_RS09370 WP_000611328.1 1969454..1970110(+) (letA) [Escherichia coli strain W21 isolate China:Kunming]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=924618 AB4O71_RS09370 WP_000611328.1 1969454..1970110(+) (letA) [Escherichia coli strain W21 isolate China:Kunming]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482