Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AB4O91_RS09665 Genome accession   NZ_CP163029
Coordinates   2027211..2027867 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain W170     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2022211..2032867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4O91_RS09630 (AB4O91_09630) dcyD 2023090..2024076 (+) 987 WP_039023114.1 D-cysteine desulfhydrase -
  AB4O91_RS09635 (AB4O91_09635) tcyL 2024091..2024759 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AB4O91_RS09640 (AB4O91_09640) tcyN 2024756..2025508 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AB4O91_RS09645 (AB4O91_09645) sdiA 2025738..2026460 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  AB4O91_RS09650 (AB4O91_09650) yecF 2026528..2026752 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AB4O91_RS09655 (AB4O91_09655) yecU 2026739..2026915 (-) 177 WP_000590344.1 protein YecU -
  AB4O91_RS09660 (AB4O91_09660) - 2026953..2027069 (-) 117 WP_001302039.1 hypothetical protein -
  AB4O91_RS09665 (AB4O91_09665) letA 2027211..2027867 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AB4O91_RS09670 (AB4O91_09670) uvrC 2027864..2029696 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AB4O91_RS09675 (AB4O91_09675) pgsA 2029753..2030301 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB4O91_RS09695 (AB4O91_09695) yecA 2030950..2031615 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=924220 AB4O91_RS09665 WP_000611328.1 2027211..2027867(+) (letA) [Escherichia coli strain W170]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=924220 AB4O91_RS09665 WP_000611328.1 2027211..2027867(+) (letA) [Escherichia coli strain W170]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482