NTDB

Overview

Name	comYH	Type	Machinery gene
Locus tag	VRA41_RS08600	Genome accession	NZ_CP142105
Coordinates	1649128..1650084 (-)	Length	318 a.a.
NCBI ID	WP_011226622.1	Uniprot ID	A0A8D6XRE9
Organism	Streptococcus thermophilus strain SCB0351
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1644128..1655084

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VRA41_RS08570 (VRA41_08570)	proC	1644678..1645448 (+)	771	WP_011226616.1	pyrroline-5-carboxylate reductase	-
VRA41_RS08575 (VRA41_08575)	-	1645478..1646140 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
VRA41_RS08580 (VRA41_08580)	-	1646243..1646691 (-)	449	Protein_1642	CAAX protease	-
VRA41_RS08585 (VRA41_08585)	-	1646765..1647190 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
VRA41_RS08590 (VRA41_08590)	-	1647433..1647630 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
VRA41_RS08595 (VRA41_08595)	-	1647879..1649072 (-)	1194	WP_022096898.1	acetate kinase	-
VRA41_RS08600 (VRA41_08600)	comYH	1649128..1650084 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
VRA41_RS08605 (VRA41_08605)	comGG	1650129..1650446 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
VRA41_RS08610 (VRA41_08610)	comYF	1650424..1650861 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
VRA41_RS08615 (VRA41_08615)	comGE	1650845..1651138 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
VRA41_RS08620 (VRA41_08620)	comYD	1651110..1651538 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
VRA41_RS08625 (VRA41_08625)	comYC	1651498..1651824 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
VRA41_RS08630 (VRA41_08630)	comYB	1651821..1652921 (-)	1101	WP_148148889.1	competence type IV pilus assembly protein ComGB	Machinery gene
VRA41_RS08635 (VRA41_08635)	comGA/cglA/cilD	1652803..1653744 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
VRA41_RS08640 (VRA41_08640)	-	1653825..1654187 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

Download Length: 318 a.a. Molecular weight: 35857.00 Da Isoelectric Point: 4.7123

                                >NTDB_id=921698 VRA41_RS08600 WP_011226622.1 1649128..1650084(-) (comYH) [Streptococcus thermophilus strain SCB0351]

MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANELIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL

EALQANHQFTPDAIGFIILYLLEGLTQEKQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIAEVVNSV

AVYIQGDAVRPHILKESNVIISDLPIGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAIFLAPTNLLTSPQ

SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTKNAPETFVYPLSDLQNPRILKDFTENFQKWKSDNSIF

Nucleotide

Download Length: 957 bp

                                >NTDB_id=921698 VRA41_RS08600 WP_011226622.1 1649128..1650084(-) (comYH) [Streptococcus thermophilus strain SCB0351]

ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACTATTGAAAATGATCTTGGAACCCA

TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTTGCTAATGAGCTCATCATCAAAAACAACG

AGAAATTACGGGCGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTTTTGTTTATCAAACTAGGGCAATTG

GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATCGGATTTATCATTCTGTACTTGCTCGAAGGTTTGACCCA

GGAAAAACAATTAGATATCTTGGAGATTGGTTCGGGAACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA

CCCTTAATTATATGGGGATGGAAGTTGATGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGAGGTGGTGAATTCAGTA

GCGGTTTATATCCAAGGGGATGCTGTTCGACCACATATTCTCAAAGAGAGCAACGTTATTATCAGCGATTTACCTATAGG

TTACTACCCTAATGATGAGATTGCGAGTCGTTTCAAGGTGGCAGCAACTGGCGAACACACTTATGCCCATCATCTTCTTA

TGGAGCAATCGCTTAAGTATTTGAAGAAAGATGGTATTGCTATTTTTTTGGCACCAACCAATCTTTTGACAAGCCCTCAA

AGTGATCTGCTTAAGAAGTGGTTATCAGGATATGCTGATATTATTGCTGTTATTACTCTTCCAGAAGCAGCTTTTGGCAA

TAAACATAACATGAAGTCTATCTTTGTGCTAAAAAAACAAACTAAAAATGCTCCTGAGACCTTCGTTTACCCACTTAGCG

ATTTGCAAAATCCAAGGATCCTCAAGGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-291)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comYH	Streptococcus mutans UA159	68.889	99.057	0.682
comYH	Streptococcus mutans UA140	68.889	99.057	0.682

Detailed information NTG0921698