Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   AB3453_RS04090 Genome accession   NZ_CP162420
Coordinates   786819..788081 (+) Length   420 a.a.
NCBI ID   WP_000472304.1    Uniprot ID   Q8NW72
Organism   Staphylococcus aureus strain TUM22741     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 781819..793081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3453_RS04055 (AB3453_04055) infC 782347..782874 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  AB3453_RS04060 (AB3453_04060) rpmI 782903..783103 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  AB3453_RS04065 (AB3453_04065) rplT 783150..783506 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  AB3453_RS04070 (AB3453_04070) - 783648..784256 (+) 609 WP_000032650.1 NUDIX domain-containing protein -
  AB3453_RS04075 (AB3453_04075) - 784275..785204 (+) 930 WP_001280022.1 hypothetical protein -
  AB3453_RS04080 (AB3453_04080) - 785209..785319 (+) 111 WP_001790560.1 hypothetical protein -
  AB3453_RS04085 (AB3453_04085) tig 785367..786668 (+) 1302 WP_000127573.1 trigger factor -
  AB3453_RS04090 (AB3453_04090) clpX 786819..788081 (+) 1263 WP_000472304.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  AB3453_RS04095 (AB3453_04095) yihA 788235..788825 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  AB3453_RS04100 (AB3453_04100) hemA 789042..790388 (+) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  AB3453_RS04105 (AB3453_04105) ccsA 790410..791225 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  AB3453_RS04110 (AB3453_04110) hemC 791267..792193 (+) 927 WP_001230226.1 hydroxymethylbilane synthase -
  AB3453_RS04115 (AB3453_04115) - 792215..792883 (+) 669 WP_117218876.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46296.49 Da        Isoelectric Point: 4.2827

>NTDB_id=921256 AB3453_RS04090 WP_000472304.1 786819..788081(+) (clpX) [Staphylococcus aureus strain TUM22741]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDNVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=921256 AB3453_RS04090 WP_000472304.1 786819..788081(+) (clpX) [Staphylococcus aureus strain TUM22741]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATAATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8NW72

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531