Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   VOI49_RS07790 Genome accession   NZ_CP142018
Coordinates   1552907..1554232 (-) Length   441 a.a.
NCBI ID   WP_003052142.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain lu24     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1547907..1559232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS07755 - 1548514..1549269 (-) 756 WP_003052128.1 hypothetical protein -
  VOI49_RS07760 - 1549280..1549975 (-) 696 WP_003052130.1 ABC transporter ATP-binding protein -
  VOI49_RS07765 - 1549988..1550176 (-) 189 WP_003052131.1 helix-turn-helix transcriptional regulator -
  VOI49_RS07770 - 1550181..1550528 (-) 348 WP_003052134.1 hypothetical protein -
  VOI49_RS07775 - 1550736..1551687 (+) 952 Protein_1473 IS30 family transposase -
  VOI49_RS07780 hpf 1551642..1552190 (-) 549 WP_003052138.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  VOI49_RS07785 - 1552270..1552935 (-) 666 WP_037585002.1 ComF family protein -
  VOI49_RS07790 comFA/cflA 1552907..1554232 (-) 1326 WP_003052142.1 DEAD/DEAH box helicase Machinery gene
  VOI49_RS07795 - 1554288..1554926 (+) 639 WP_003052144.1 YigZ family protein -
  VOI49_RS07800 cysK 1555030..1555965 (+) 936 WP_003052146.1 cysteine synthase A -
  VOI49_RS07805 - 1556116..1556475 (-) 360 WP_003052148.1 S1 RNA-binding domain-containing protein -
  VOI49_RS07810 - 1556475..1557876 (-) 1402 Protein_1480 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  VOI49_RS07815 - 1557913..1558554 (-) 642 WP_003052152.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49359.45 Da        Isoelectric Point: 9.6283

>NTDB_id=921028 VOI49_RS07790 WP_003052142.1 1552907..1554232(-) (comFA/cflA) [Streptococcus dysgalactiae strain lu24]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVIIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYASQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDDFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYSNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=921028 VOI49_RS07790 WP_003052142.1 1552907..1554232(-) (comFA/cflA) [Streptococcus dysgalactiae strain lu24]
ATGGAAGGTATTGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAATCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGCGGCACTTACTACTGTCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACACCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGTAAGACAGAGATGATTTATGGTGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCTAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGAGTTACTCTTTTACACGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCATCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAATTAGAGAAGTTGACATTAGCTAGACGATTTCATGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGCCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAGCAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGACTT
TCGTCAAGGAAAGAAAGGCATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGTGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTCGGGAGATCTATCGAAAGG
CCAACAGGAAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTCGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(99-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae D39

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae R6

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae TIGR4

53.081

95.692

0.508
  comFA/cflA Streptococcus mitis NCTC 12261

51.628

97.506

0.503
  comFA/cflA Streptococcus mitis SK321

51.765

96.372

0.499
  comFA Lactococcus lactis subsp. cremoris KW2

45.366

92.971

0.422
  comFA Latilactobacillus sakei subsp. sakei 23K

37.355

97.732

0.365