Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VKS18_RS05760 Genome accession   NZ_CP141895
Coordinates   1115125..1115781 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain B004     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1110125..1120781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKS18_RS05730 (VKS18_15155) oppF 1110655..1111572 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  VKS18_RS05735 (VKS18_15160) - 1111679..1112866 (+) 1188 WP_079891125.1 putative glycoside hydrolase -
  VKS18_RS05740 (VKS18_15165) - 1112984..1113562 (+) 579 WP_032874457.1 GNAT family N-acetyltransferase -
  VKS18_RS05745 (VKS18_15170) spx 1113741..1114136 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  VKS18_RS05750 (VKS18_15175) - 1114193..1114849 (-) 657 WP_032874459.1 TerC family protein -
  VKS18_RS05755 (VKS18_15180) - 1115032..1115142 (+) 111 Protein_1071 adaptor protein MecA -
  VKS18_RS05760 (VKS18_15185) mecA 1115125..1115781 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  VKS18_RS05765 (VKS18_15190) - 1115932..1117092 (+) 1161 WP_032874460.1 competence protein CoiA family protein -
  VKS18_RS05770 (VKS18_15195) pepF 1117320..1119149 (+) 1830 WP_087920792.1 oligoendopeptidase F Regulator
  VKS18_RS05775 (VKS18_15200) - 1119187..1119354 (-) 168 WP_032874462.1 hypothetical protein -
  VKS18_RS05780 (VKS18_15205) spxH 1119640..1120542 (-) 903 WP_032874464.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=920352 VKS18_RS05760 WP_003155032.1 1115125..1115781(+) (mecA) [Bacillus velezensis strain B004]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=920352 VKS18_RS05760 WP_003155032.1 1115125..1115781(+) (mecA) [Bacillus velezensis strain B004]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAGA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895