Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   VF946_RS04595 Genome accession   NZ_CP141824
Coordinates   850796..852022 (-) Length   408 a.a.
NCBI ID   WP_015646860.1    Uniprot ID   A0A0Z8EVL4
Organism   Streptococcus suis strain HB18     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 845796..857022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS04565 - 845831..846055 (-) 225 WP_002934981.1 hypothetical protein -
  VF946_RS04570 - 846116..847423 (-) 1308 WP_172011581.1 excalibur calcium-binding domain-containing protein -
  VF946_RS04575 - 847558..847740 (+) 183 WP_044670667.1 4-oxalocrotonate tautomerase -
  VF946_RS04580 lepA 847790..849622 (-) 1833 WP_002943192.1 translation elongation factor 4 -
  VF946_RS04585 ndk 849718..850131 (-) 414 WP_105148475.1 nucleoside-diphosphate kinase -
  VF946_RS04590 yihA 850154..850741 (-) 588 WP_238716799.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  VF946_RS04595 clpX 850796..852022 (-) 1227 WP_015646860.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  VF946_RS04600 - 852220..852732 (-) 513 WP_238716800.1 dihydrofolate reductase -
  VF946_RS04605 - 852976..853815 (-) 840 WP_238716801.1 thymidylate synthase -
  VF946_RS04610 - 853868..854170 (-) 303 WP_024410080.1 hypothetical protein -
  VF946_RS04615 - 854182..854460 (-) 279 WP_012775087.1 hypothetical protein -
  VF946_RS04620 - 854587..855546 (-) 960 WP_014637956.1 ROK family glucokinase -
  VF946_RS04625 - 855638..855973 (-) 336 WP_024410081.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45309.83 Da        Isoelectric Point: 4.5987

>NTDB_id=919752 VF946_RS04595 WP_015646860.1 850796..852022(-) (clpX) [Streptococcus suis strain HB18]
MAVKHTQELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=919752 VF946_RS04595 WP_015646860.1 850796..852022(-) (clpX) [Streptococcus suis strain HB18]
ATGGCTGTTAAGCATACACAAGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAATAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACACCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTTCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATTGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8EVL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574