Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   VNN51_RS01335 Genome accession   NZ_CP141727
Coordinates   271195..272685 (-) Length   496 a.a.
NCBI ID   WP_017368871.1    Uniprot ID   A0A9X4P077
Organism   Lactococcus formosensis strain M20011502 FF20a2     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 266195..277685
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN51_RS01320 (VNN51_01320) murD 266990..268351 (-) 1362 WP_253008109.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  VNN51_RS01325 (VNN51_01325) - 268490..269227 (-) 738 WP_017368873.1 amino acid ABC transporter ATP-binding protein -
  VNN51_RS01330 (VNN51_01330) - 269228..270799 (-) 1572 WP_017368872.1 ABC transporter permease subunit -
  VNN51_RS01335 (VNN51_01335) covS 271195..272685 (-) 1491 WP_017368871.1 HAMP domain-containing histidine kinase Regulator
  VNN51_RS01340 (VNN51_01340) covR 272773..273468 (-) 696 WP_017368870.1 response regulator transcription factor Regulator
  VNN51_RS01345 (VNN51_01345) - 273569..274120 (-) 552 WP_279359205.1 YceD family protein -
  VNN51_RS01350 (VNN51_01350) - 274338..274580 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN51_RS01355 (VNN51_01355) - 274692..276596 (-) 1905 WP_279360506.1 fructose-specific PTS transporter subunit EIIC -
  VNN51_RS01360 (VNN51_01360) pfkB 276630..277547 (-) 918 WP_279359203.1 1-phosphofructokinase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56906.83 Da        Isoelectric Point: 4.9901

>NTDB_id=919013 VNN51_RS01335 WP_017368871.1 271195..272685(-) (covS) [Lactococcus formosensis strain M20011502 FF20a2]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMRALNNVEQSLSQSANKLS
EENLANYLAYAKDYTASSQGRENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSSQAVRTFGEYSGYLV
ERPVHSKKTGELIGYVQAFYDMSYYYSVRTKLLVALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLKLTVENDLSSGRLAHIYPNHYEQGLKILIDNAI
KYSPEDRQEVKIHLEEDDEYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYEGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=919013 VNN51_RS01335 WP_017368871.1 271195..272685(-) (covS) [Lactococcus formosensis strain M20011502 FF20a2]
ATGGTAAAATTTTTTGATTCTAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGTTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACTTTCACTATTTTTACAGTATTGGTTTATCAACTAACGATAACTACTTTCA
TCAATTCTGAAAAAGAGGATATGATGAGGGCTTTAAATAATGTTGAACAAAGTCTGTCCCAATCGGCAAACAAACTGTCA
GAAGAAAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCCTCCAGTCAGGGAAGAGAAAATGAACTTGAAAC
ACTAGGAAGTATGATTGGTTCAAGAAAGTCCTTTTATGTCTTTGATGTGGGTGAAAATCTGATCTACTCGACCAATTCGT
ATGGTTTTCCGCTAAGGAAAGATGTGGGTGATTCATCGCAAGCTGTACGTACATTTGGCGAATATTCTGGTTATTTGGTT
GAGCGACCTGTGCATTCTAAAAAAACGGGTGAACTGATCGGCTATGTACAGGCTTTTTATGATATGAGCTATTATTATAG
TGTGCGTACAAAGCTACTAGTTGCCTTGATTATCTTAGAAATTATAGCACTCTTTATTGCTCAGTTTGTTGGTTACTTTA
TGGCGAGCCGCTATATCAAGCCTTTGGAACGTTTGCACGATGCAATCACTACACGTGCCAATAATTTGAAGGCAGATTTC
AAACCTGTCGTTATTCAGACAGGGGATGAAATTGAAGAACTTGCAACAGTTTATAATGATATGATGATCAAGCTTAATGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCCGATGTCAGTCATGAGTTACGGACGCCACTTGCAGTTTTGGATGGGCATT
TGAATCTCTTGAATCGTTGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGT
ACGATGAGAACGATGTTGGAAGAAATGCTCGCATTGGCACGTCTTGAAAGCATTGATTTTCAAGATGAAGACCTAATCTG
TGATCCGACAGAAGTTTCGAATTTTCTTAAGAAAAATTTTCTACTCATTCATCCTGATTTAAAGTTAACTGTTGAAAATG
ACTTGTCATCAGGAAGATTAGCACATATATACCCCAACCATTATGAGCAAGGTTTGAAAATATTGATCGATAATGCGATA
AAATACTCGCCTGAAGATCGTCAAGAAGTCAAGATACATCTTGAAGAAGATGATGAATATATCATTACAACTGTGGAGGA
CCGTGGTTATGGTATTAGCCAAGAAGATTTAAAACATGTATTTGAACGTTTCTTCCGTGCGGATAAAGCGCGAAATCGAG
ATATAGGAGGCACTGGGCTTGGGTTATCTATTATTCAACGTATAGTGGAGAACTATGAGGGGGATGTTAGCGTGACCTCC
GTTGTAGGAGAGGGTTCAAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)

HAMP domain (HAMP)

(214-266)

ArlS sensor domain (ArlS_N)

(52-190)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

55.533

100

0.556