Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VNN46_RS01525 Genome accession   NZ_CP141719
Coordinates   310234..310917 (-) Length   227 a.a.
NCBI ID   WP_004259224.1    Uniprot ID   A0A1I4FNQ8
Organism   Lactococcus garvieae strain CAHFS22LA20.5H7     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 305234..315917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN46_RS01505 (VNN46_01505) - 305587..306798 (-) 1212 WP_265150251.1 cysteine desulfurase -
  VNN46_RS01510 (VNN46_01510) sufD 306798..308054 (-) 1257 WP_019299087.1 Fe-S cluster assembly protein SufD -
  VNN46_RS01515 (VNN46_01515) sufC 308126..308896 (-) 771 WP_014024332.1 Fe-S cluster assembly ATPase SufC -
  VNN46_RS01520 (VNN46_01520) - 308974..310230 (-) 1257 WP_014024331.1 glycosyltransferase family 4 protein -
  VNN46_RS01525 (VNN46_01525) mecA 310234..310917 (-) 684 WP_004259224.1 adaptor protein MecA Regulator
  VNN46_RS01530 (VNN46_01530) - 311161..312069 (+) 909 WP_265150243.1 diacylglycerol kinase family protein -
  VNN46_RS01535 (VNN46_01535) rpoC 312164..315811 (-) 3648 WP_004259228.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26239.38 Da        Isoelectric Point: 4.0202

>NTDB_id=918790 VNN46_RS01525 WP_004259224.1 310234..310917(-) (mecA) [Lactococcus garvieae strain CAHFS22LA20.5H7]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYQDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETVNSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=918790 VNN46_RS01525 WP_004259224.1 310234..310917(-) (mecA) [Lactococcus garvieae strain CAHFS22LA20.5H7]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACTAACCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAGCTAGGACTTGAGGAAAGAT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATCATTGTTACCGAGGAAAATATTGAT
ATTGATCCCAATAATCTCCCGGATGATCCTGAAGAATTTGAGCAGCTGATGACGGATTTCTTTGGGCGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACGAAAGAAACAAAAGTAGAAAATAAACCAGACCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAATATGTCTCAACTTTTGACAGCAGTAAAAAATGTTAAAATTGATGCAGAA
GAGTCTGAACTTTACAGTTACCAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAATCAAAAGGAAAAACAGCCGT
AAGTTCGATGCGTGCCCGAATGTTAGAATATGGCCAGGAAACGGTCAACAGTCGTGAAACCCTACAAGAATACGGCGAGA
TACTAATCAATACGCGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FNQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.661

100

0.568
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555