Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VNN36_RS01835 Genome accession   NZ_CP141717
Coordinates   359558..360241 (-) Length   227 a.a.
NCBI ID   WP_004259224.1    Uniprot ID   A0A1I4FNQ8
Organism   Lactococcus garvieae strain R22-8     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 354558..365241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN36_RS01815 (VNN36_01815) - 354912..356123 (-) 1212 WP_339013718.1 cysteine desulfurase -
  VNN36_RS01820 (VNN36_01820) sufD 356123..357379 (-) 1257 WP_019299087.1 Fe-S cluster assembly protein SufD -
  VNN36_RS01825 (VNN36_01825) sufC 357451..358221 (-) 771 WP_339013721.1 Fe-S cluster assembly ATPase SufC -
  VNN36_RS01830 (VNN36_01830) - 358298..359554 (-) 1257 WP_042217292.1 MraY family glycosyltransferase -
  VNN36_RS01835 (VNN36_01835) mecA 359558..360241 (-) 684 WP_004259224.1 adaptor protein MecA Regulator
  VNN36_RS01840 (VNN36_01840) - 360485..361393 (+) 909 WP_339013726.1 diacylglycerol kinase family protein -
  VNN36_RS01845 (VNN36_01845) rpoC 361487..365134 (-) 3648 WP_004259228.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26239.38 Da        Isoelectric Point: 4.0202

>NTDB_id=918747 VNN36_RS01835 WP_004259224.1 359558..360241(-) (mecA) [Lactococcus garvieae strain R22-8]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYQDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETVNSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=918747 VNN36_RS01835 WP_004259224.1 359558..360241(-) (mecA) [Lactococcus garvieae strain R22-8]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACTAACCAGTCGATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAGCTAGGACTTGAGGAAAGAT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATCATTGTTACTGAGGAAAACATTGAT
ATTGATCCCAATAATCTCCCGGATGATCCTGAAGAATTTGAGCAGCTGATGACGGATTTCTTTGGGCGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACGAAAGAAACAAAAGTAGAAAATAAACCAGACCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAATATGTCTCAACTTTTGACAGCGGTAAAAAATGTTAAAATTGATGCAGAA
GAGTCTGAACTTTACAGTTACCAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAATCAAAAGGAAAAACAGCTGT
AAGTTCGATGCGTGCCCGAATGTTAGAATACGGCCAGGAAACGGTCAACAGTCGTGAAACCCTACAAGAATACGGCGAGA
TACTAATCAATACGCGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FNQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.661

100

0.568
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555