Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VNN27_RS01540 Genome accession   NZ_CP141700
Coordinates   311757..312440 (-) Length   227 a.a.
NCBI ID   WP_019292408.1    Uniprot ID   A0A139MDU9
Organism   Lactococcus petauri strain R22-25 IC35     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 306757..317440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN27_RS01520 (VNN27_01520) - 307110..308321 (-) 1212 WP_019292404.1 cysteine desulfurase -
  VNN27_RS01525 (VNN27_01525) sufD 308321..309577 (-) 1257 WP_019293599.1 Fe-S cluster assembly protein SufD -
  VNN27_RS01530 (VNN27_01530) sufC 309649..310419 (-) 771 WP_017368843.1 Fe-S cluster assembly ATPase SufC -
  VNN27_RS01535 (VNN27_01535) - 310497..311753 (-) 1257 WP_019292407.1 MraY family glycosyltransferase -
  VNN27_RS01540 (VNN27_01540) mecA 311757..312440 (-) 684 WP_019292408.1 adaptor protein MecA Regulator
  VNN27_RS01545 (VNN27_01545) - 312687..313595 (+) 909 WP_019292409.1 diacylglycerol kinase family protein -
  VNN27_RS01550 (VNN27_01550) rpoC 313688..317335 (-) 3648 WP_019292410.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26254.39 Da        Isoelectric Point: 4.0031

>NTDB_id=918478 VNN27_RS01540 WP_019292408.1 311757..312440(-) (mecA) [Lactococcus petauri strain R22-25 IC35]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYEDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETINSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=918478 VNN27_RS01540 WP_019292408.1 311757..312440(-) (mecA) [Lactococcus petauri strain R22-25 IC35]
ATGCAATATGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACGAACCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAACTAGGACTTGAGGAAAGGT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATTATTGTTACTGAAGAAAATATTGAT
ATTGATCCCAATAATCTCCCTGATGATCCCGAAGAATTTGAGCAGCTTATGACGGATTTCTTTGGACGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACAAAAGAAACAAAAGTAGAAAATAAACCAGATCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAACATGTCTCAACTTTTGACAGCAGTAAAAAATGTTAAAATTGATGCAGAG
GAATCTGAACTTTATAGCTATGAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAGTCAAAAGGAAAGACAGCAGT
AAGTTCGATGCGTGCCCGAATGTTAGAATACGGACAGGAAACAATCAACAGTCGCGAAACACTACAAGAATACGGCGAGA
TACTAATCAATACACGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139MDU9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.077

100

0.555
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555