Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   ABXJ52_RS20570 Genome accession   NZ_CP160402
Coordinates   4534140..4535264 (-) Length   374 a.a.
NCBI ID   WP_249588570.1    Uniprot ID   A0ABY4PW39
Organism   Streptomyces sp. Je 1-332     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4529140..4540264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXJ52_RS20550 (ABXJ52_20550) - 4530155..4531768 (+) 1614 WP_367044072.1 histidine kinase -
  ABXJ52_RS20555 (ABXJ52_20555) - 4531765..4532418 (+) 654 WP_367044073.1 response regulator transcription factor -
  ABXJ52_RS20560 (ABXJ52_20560) - 4532422..4533078 (-) 657 WP_367044074.1 phosphatase PAP2 family protein -
  ABXJ52_RS20565 (ABXJ52_20565) - 4533264..4534082 (+) 819 WP_367044075.1 hypothetical protein -
  ABXJ52_RS20570 (ABXJ52_20570) disA 4534140..4535264 (-) 1125 WP_249588570.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  ABXJ52_RS20575 (ABXJ52_20575) radA/sms 4535345..4536754 (-) 1410 WP_367044076.1 DNA repair protein RadA Machinery gene
  ABXJ52_RS20580 (ABXJ52_20580) - 4536932..4538641 (+) 1710 WP_367044077.1 hypothetical protein -
  ABXJ52_RS20585 (ABXJ52_20585) - 4538722..4539555 (-) 834 WP_367044078.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40265.15 Da        Isoelectric Point: 4.9339

>NTDB_id=918280 ABXJ52_RS20570 WP_249588570.1 4534140..4535264(-) (disA) [Streptomyces sp. Je 1-332]
MAANDRASAPGKPGGSSGAEGLMRASLSAVAPGTGLRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVVDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPIVSVSQSMRLIALYVDGQRKVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVEEALFELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=918280 ABXJ52_RS20570 WP_249588570.1 4534140..4535264(-) (disA) [Streptomyces sp. Je 1-332]
GTGGCAGCCAACGACCGGGCGTCAGCTCCCGGCAAGCCCGGCGGAAGCTCCGGTGCCGAAGGGCTGATGCGCGCCTCTCT
GAGCGCGGTCGCGCCCGGCACCGGCCTGCGCGACGGACTGGAGCGCATCCTCCGCGGCAACACCGGAGGGCTCATCGTCC
TCGGCTGGGACAAGACCGTCGAATCGATGTGTACGGGCGGATTCATCCTGGATGTCGAGTTCACGGCGACGCGGTTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCGTCGACAAGGACATCACCAAGATTCTGCGCGCGGGCGTGCAGCTCGTCCC
CGACCCGACGATCCCCACGGAGGAGACGGGCACCCGGCACCGCACCGCGGACCGCGTGTCCAAGCAGGTGGGCTTCCCCA
TCGTCTCCGTCTCCCAGTCGATGCGCCTCATCGCGCTCTACGTGGACGGACAGCGCAAGGTCCTCGAGGACTCGGCGGCG
ATCCTGTCCCGCGCGAACCAGGCCCTCGCGACCCTGGAGCGGTACAAACTGCGCCTCGACGAGGTGGCGGGCACGCTCTC
CGCCCTGGAGATCGAGGACTTGGTGACGGTCCGCGATGTCACGGCGGTCGCCCAGCGCCTGGAGATGGTGCGCCGCATCG
CCACGGAAATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGCCGGCTTCTCGCCCTCCAGCTGGACGAGTTGATCGCG
GGCGTCGAGCCCGAGCGTGAACTGGTCGTCAGGGACTACGTCCCGGAGCCGACGGCCAAGCGCTCCCGCACGGTCGAGGA
GGCGCTCTTCGAGCTGGACGCGCTGAGCCATGCGGAGCTGCTCGAACTGCCCACCGTGGCACGGGCGTTGGGTTACACCG
GCTCCCCGGAAGCGCTGGACTCCGCCGTCTCGCCGCGGGGCTTCCGACTGCTCGCCAAGGTGCCGCGTCTTCCCGGCGCG
ATCATCGACCGGCTCGTGGAGCACTTCGGGGGGCTGCAGAAGCTTCTCGCTGCGAGCGTCGATGACTTGCAGACGGTCGA
CGGGGTCGGGGAAGCGCGGGCCCGGAGTGTGCGCGAGGGGCTCTCGCGGCTTGCCGAGTCCTCGATTCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.954

92.513

0.425