Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABXJ52_RS11485 Genome accession   NZ_CP160402
Coordinates   2473570..2474241 (+) Length   223 a.a.
NCBI ID   WP_367041544.1    Uniprot ID   -
Organism   Streptomyces sp. Je 1-332     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2468570..2479241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXJ52_RS11465 (ABXJ52_11465) - 2469036..2469653 (+) 618 WP_367048985.1 TetR family transcriptional regulator -
  ABXJ52_RS11470 (ABXJ52_11470) - 2469916..2471127 (+) 1212 WP_367041538.1 alpha/beta hydrolase -
  ABXJ52_RS11475 (ABXJ52_11475) - 2471203..2472075 (+) 873 WP_367041540.1 DUF4429 domain-containing protein -
  ABXJ52_RS11480 (ABXJ52_11480) - 2472209..2473573 (+) 1365 WP_367041542.1 histidine kinase -
  ABXJ52_RS11485 (ABXJ52_11485) vraR 2473570..2474241 (+) 672 WP_367041544.1 response regulator transcription factor Regulator
  ABXJ52_RS11490 (ABXJ52_11490) - 2474390..2475607 (+) 1218 WP_367041546.1 alpha/beta hydrolase -
  ABXJ52_RS11495 (ABXJ52_11495) - 2475604..2476833 (+) 1230 WP_367041548.1 acyltransferase -
  ABXJ52_RS11500 (ABXJ52_11500) - 2477160..2478209 (-) 1050 WP_367048987.1 aldo/keto reductase -
  ABXJ52_RS11505 (ABXJ52_11505) - 2478269..2478853 (-) 585 WP_367041550.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24068.80 Da        Isoelectric Point: 5.0891

>NTDB_id=918252 ABXJ52_RS11485 WP_367041544.1 2473570..2474241(+) (vraR) [Streptomyces sp. Je 1-332]
MTIRVIIVDDQNMVRAGFAALLAAQSDIDVVGEAPNGKAAVDVSRNTHPDVVLMDVRMPEMDGLTAARALLDPPPGVVHV
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGDALLAPSVTRRLITDFAKQRPRTDQSLRLNGLTQ
RETEVLVLIARGLSNQEIAERLVLAEQTVKTHIGKVLSKLDLRDRAQAVIFAYESGLITPGEQ

Nucleotide


Download         Length: 672 bp        

>NTDB_id=918252 ABXJ52_RS11485 WP_367041544.1 2473570..2474241(+) (vraR) [Streptomyces sp. Je 1-332]
ATGACCATCCGCGTGATCATCGTCGATGACCAGAACATGGTGCGGGCCGGCTTCGCCGCACTCCTCGCGGCGCAGAGCGA
CATCGACGTCGTGGGCGAGGCGCCGAACGGCAAGGCGGCTGTCGACGTCAGCCGCAACACCCATCCCGATGTCGTCCTGA
TGGATGTCCGGATGCCCGAGATGGACGGACTCACCGCGGCTCGCGCCCTGTTGGACCCTCCGCCCGGAGTGGTGCACGTG
CCGAAGGTGCTGATGCTCACCACCTTCGACGTGGACGACTATGTGTACGAGGCGCTGCGCGCCGGAGCCTCGGGCTTCCT
CCTCAAGGACGCTCCGCCCGCCGATCTGATCTCGGCGGTCCGCGTGGTGGCGGCCGGCGACGCGCTGCTCGCTCCATCGG
TGACACGCCGCCTGATCACGGACTTCGCCAAGCAACGGCCGCGCACCGACCAGTCGCTGCGACTGAACGGCCTGACACAG
CGTGAGACCGAGGTACTGGTGCTGATCGCGCGCGGCCTGTCGAATCAGGAGATCGCCGAGCGCCTGGTCCTCGCCGAACA
GACCGTGAAGACCCATATCGGCAAGGTGCTGTCCAAGTTGGACCTGCGGGACCGCGCGCAAGCCGTGATCTTCGCCTACG
AGTCAGGACTGATCACGCCCGGGGAGCAGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.379

98.206

0.426
  degU Bacillus subtilis subsp. subtilis str. 168

36.564

100

0.372