Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABXJ52_RS08535 Genome accession   NZ_CP160402
Coordinates   1827800..1828468 (+) Length   222 a.a.
NCBI ID   WP_367040603.1    Uniprot ID   -
Organism   Streptomyces sp. Je 1-332     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1822800..1833468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXJ52_RS08510 (ABXJ52_08510) - 1822988..1824517 (-) 1530 WP_367040596.1 aldehyde dehydrogenase (NADP(+)) -
  ABXJ52_RS08515 (ABXJ52_08515) - 1824654..1825424 (+) 771 WP_160504308.1 IclR family transcriptional regulator -
  ABXJ52_RS08520 (ABXJ52_08520) - 1825457..1825927 (+) 471 WP_367048905.1 GNAT family N-acetyltransferase -
  ABXJ52_RS08525 (ABXJ52_08525) - 1826077..1826529 (+) 453 WP_367040600.1 hypothetical protein -
  ABXJ52_RS08530 (ABXJ52_08530) - 1826526..1827803 (+) 1278 WP_367040601.1 histidine kinase -
  ABXJ52_RS08535 (ABXJ52_08535) vraR 1827800..1828468 (+) 669 WP_367040603.1 response regulator transcription factor Regulator
  ABXJ52_RS08540 (ABXJ52_08540) - 1828552..1830000 (+) 1449 WP_367040604.1 penicillin-binding transpeptidase domain-containing protein -
  ABXJ52_RS08545 (ABXJ52_08545) - 1830103..1830897 (-) 795 WP_367040605.1 HAD family acid phosphatase -
  ABXJ52_RS08550 (ABXJ52_08550) - 1831049..1831639 (-) 591 WP_367040606.1 TIGR03086 family metal-binding protein -
  ABXJ52_RS08555 (ABXJ52_08555) - 1831823..1833052 (+) 1230 WP_367040607.1 MFS transporter -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23599.07 Da        Isoelectric Point: 5.1366

>NTDB_id=918244 ABXJ52_RS08535 WP_367040603.1 1827800..1828468(+) (vraR) [Streptomyces sp. Je 1-332]
MTETAAPSIRIVLADDERMVRTALRVILSAEPDLEVVGEAASGAEAVSVVREAQPDVVLMDVRMPEIDGIRATEQILRTQ
ADPPRIVVVTTFENDSYVYEALRAGASGFLLKRADADSLVQAVRLVARSDSLLFPAAVRALAAEHARAKPAPPAWVARLT
GRESEVLRLMAAGLTNAEIAGRMGVGPATVKTHVASVLAKTGTRDRTQAVIAAYEAGFMNAD

Nucleotide


Download         Length: 669 bp        

>NTDB_id=918244 ABXJ52_RS08535 WP_367040603.1 1827800..1828468(+) (vraR) [Streptomyces sp. Je 1-332]
ATGACCGAGACGGCAGCCCCCTCGATCCGCATCGTGCTCGCCGACGACGAACGCATGGTCCGCACCGCCCTGCGCGTGAT
CCTCTCCGCCGAGCCCGACCTGGAGGTCGTCGGCGAGGCGGCGAGCGGCGCGGAGGCGGTGTCCGTCGTGCGCGAGGCGC
AGCCCGACGTGGTGCTCATGGACGTACGGATGCCGGAGATCGACGGCATCCGGGCCACCGAGCAGATCCTGCGGACGCAG
GCCGACCCGCCGCGGATCGTGGTCGTGACGACCTTCGAGAACGACTCCTACGTGTACGAGGCGCTGCGCGCGGGGGCCTC
CGGGTTCCTGCTCAAGCGGGCCGACGCGGACTCACTCGTACAGGCGGTTCGGCTCGTGGCGCGCAGTGACTCGCTGCTCT
TCCCCGCGGCGGTGCGCGCCCTGGCCGCCGAGCACGCGCGCGCGAAGCCCGCGCCGCCGGCCTGGGTGGCGAGGCTGACG
GGGCGCGAGAGCGAGGTGCTGCGGCTGATGGCGGCGGGCCTGACGAACGCGGAGATCGCAGGCCGGATGGGGGTGGGTCC
GGCGACGGTGAAGACGCACGTGGCGTCGGTGCTGGCCAAGACGGGGACGCGGGACCGCACGCAGGCGGTGATCGCGGCGT
ACGAGGCGGGTTTCATGAACGCCGACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-212)

Response regulator receiver domain (Response_reg)

(11-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.535

96.847

0.383
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.365