Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   VNN43_RS01720 Genome accession   NZ_CP141685
Coordinates   337036..338526 (-) Length   496 a.a.
NCBI ID   WP_019293246.1    Uniprot ID   A0AAJ2ML94
Organism   Lactococcus petauri strain R21-69 HC     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 332036..343526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN43_RS01705 (VNN43_01705) murD 332830..334191 (-) 1362 WP_165719432.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  VNN43_RS01710 (VNN43_01710) - 334331..335068 (-) 738 WP_019292074.1 amino acid ABC transporter ATP-binding protein -
  VNN43_RS01715 (VNN43_01715) - 335069..336640 (-) 1572 WP_019293245.1 ABC transporter permease subunit -
  VNN43_RS01720 (VNN43_01720) covS 337036..338526 (-) 1491 WP_019293246.1 HAMP domain-containing histidine kinase Regulator
  VNN43_RS01725 (VNN43_01725) covR 338614..339309 (-) 696 WP_019292077.1 response regulator transcription factor Regulator
  VNN43_RS01730 (VNN43_01730) - 339411..339962 (-) 552 WP_206888295.1 YceD family protein -
  VNN43_RS01735 (VNN43_01735) - 340179..340421 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN43_RS01740 (VNN43_01740) - 340533..342437 (-) 1905 WP_019293248.1 fructose-specific PTS transporter subunit EIIC -
  VNN43_RS01745 (VNN43_01745) pfkB 342452..343378 (-) 927 WP_165719430.1 1-phosphofructokinase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56888.98 Da        Isoelectric Point: 5.2995

>NTDB_id=917980 VNN43_RS01720 WP_019293246.1 337036..338526(-) (covS) [Lactococcus petauri strain R21-69 HC]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=917980 VNN43_RS01720 WP_019293246.1 337036..338526(-) (covS) [Lactococcus petauri strain R21-69 HC]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCTTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGACATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTTTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTGGAAGAAGATGACAAATACATTATTACAACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(214-266)

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)

ArlS sensor domain (ArlS_N)

(52-190)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

55.823

100

0.56