Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABYD38_RS17350 Genome accession   NZ_CP159877
Coordinates   3380244..3380900 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 12867     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3375244..3385900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABYD38_RS17310 (ABYD38_17310) - 3375756..3376016 (+) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -
  ABYD38_RS17315 (ABYD38_17315) - 3376207..3376347 (+) 141 WP_000078920.1 Hok/Gef family protein -
  ABYD38_RS17320 (ABYD38_17320) - 3376536..3376817 (-) 282 WP_001303543.1 hypothetical protein -
  ABYD38_RS17340 (ABYD38_17340) pgsA 3377810..3378358 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABYD38_RS17345 (ABYD38_17345) uvrC 3378415..3380247 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  ABYD38_RS17350 (ABYD38_17350) letA 3380244..3380900 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABYD38_RS17355 (ABYD38_17355) - 3381042..3381158 (+) 117 WP_001302039.1 hypothetical protein -
  ABYD38_RS17360 (ABYD38_17360) yecU 3381196..3381372 (+) 177 WP_001342215.1 protein YecU -
  ABYD38_RS17365 (ABYD38_17365) yecF 3381359..3381583 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABYD38_RS17370 (ABYD38_17370) sdiA 3381651..3382373 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  ABYD38_RS17375 (ABYD38_17375) tcyN 3382603..3383355 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABYD38_RS17380 (ABYD38_17380) tcyL 3383352..3384020 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ABYD38_RS17385 (ABYD38_17385) dcyD 3384035..3385021 (-) 987 WP_001128238.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=915463 ABYD38_RS17350 WP_000611328.1 3380244..3380900(-) (letA) [Escherichia coli strain 12867]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=915463 ABYD38_RS17350 WP_000611328.1 3380244..3380900(-) (letA) [Escherichia coli strain 12867]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482