Detailed information NTG0912708

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ABII15_RS17155
• Genome accession: NZ_CP159534
• Coordinates: 3809720..3810844 (+)
• Length: 374 a.a.
• NCBI ID: WP_353943201.1
• Uniprot ID: A0AAU8ITR0
• Organism: Streptomyces sp. HUAS MG91
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3804720..3815844

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABII15_RS17140 (ABII15_17140)	-	3805447..3806298 (+)	852	WP_353943198.1	hypothetical protein	-
ABII15_RS17145 (ABII15_17145)	-	3806338..3808041 (-)	1704	WP_353943199.1	hypothetical protein	-
ABII15_RS17150 (ABII15_17150)	radA	3808208..3809626 (+)	1419	WP_353943200.1	DNA repair protein RadA	Machinery gene
ABII15_RS17155 (ABII15_17155)	disA	3809720..3810844 (+)	1125	WP_353943201.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ABII15_RS17160 (ABII15_17160)	-	3810966..3811790 (-)	825	WP_353943202.1	hypothetical protein	-
ABII15_RS17165 (ABII15_17165)	-	3811979..3812638 (+)	660	WP_353943203.1	phosphatase PAP2 family protein	-
ABII15_RS17170 (ABII15_17170)	-	3812913..3813827 (+)	915	WP_353943204.1	A/G-specific adenine glycosylase	-
ABII15_RS17175 (ABII15_17175)	-	3814026..3814580 (+)	555	WP_353943205.1	SigE family RNA polymerase sigma factor	-
ABII15_RS17180 (ABII15_17180)	-	3814670..3815302 (+)	633	WP_353947094.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40103.78 Da
• Isoelectric Point: 5.0029

>NTDB_id=912708 ABII15_RS17155 WP_353943201.1 3809720..3810844(+) (disA) [Streptomyces sp. HUAS MG91]
MAANDRANAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGSDRTVESMCTGGFVLDVEFSATRLR
ELCKLDGGIVVSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALSELDSLHHGELLELPIVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=912708 ABII15_RS17155 WP_353943201.1 3809720..3810844(+) (disA) [Streptomyces sp. HUAS MG91]
GTGGCAGCCAACGACCGGGCGAACGCTCCCGGCAAGTCCGGCGGGAGTTCCGGTGCGGACGGTCTGATGCGCGCCTCACT
GAGCGCGGTGGCGCCCGGTACGGCCCTGCGCGACGGCCTGGAGCGCATCCTCCGCGGCAACACCGGCGGTCTCATCGTCC
TCGGCTCCGACCGGACCGTGGAGTCGATGTGCACCGGCGGTTTCGTCCTGGACGTGGAGTTCTCCGCCACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGGTCTCCTCCGACCTCAGCAAGATCCTGCGGGCCGGTGTGCAGCTGGTGCC
GGACCCGACGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTCAGCAAGCAGGTCGGCTTCCCGG
TGGTCTCCGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGCAGCGCCGGGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGGGCGAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTGCGGCTCGACGAGGTGGCGGGCACGCTCTC
CGCCCTGGAGATCGAGGACTTGGTCACGGTCCGGGACGTCACGGCCGTCGCGCAGCGCCTGGAGATGGTGCGCCGGATCG
CCACGGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGGCGGTTGCTGGCGCTCCAGCTCGACGAGTTGATCGCG
GGCGTGGAGCCCGAGCGCGAGCTGGTCGTACGGGACTACGTGCCCGAGCCGACCGCCAAGCGCTCCCGCACGGTCGACGA
GGCGCTCTCGGAGCTGGACTCGCTGCACCACGGCGAGCTGCTCGAACTGCCCATCGTGGCGCGGGCGCTGGGGTACACGG
GATCGCCGGAGGCGCTGGACTCGGCCGTCTCGCCGCGCGGGTTCCGGCTCCTCGCCAAGGTGCCGCGGCTGCCCGGGGCC
ATCATCGACCGTCTCGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTCCAGACCGTGGA
CGGGGTCGGGGAGGCACGGGCCCGCAGCGTGCGGGAGGGGCTTTCGCGGCTTGCGGAGTCGTCGATTCTGGAGCGTTACG
TGTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: A0AAU8ITR0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.706	96.524	0.441