Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABII15_RS08820 Genome accession   NZ_CP159534
Coordinates   1912157..1912798 (-) Length   213 a.a.
NCBI ID   WP_353941718.1    Uniprot ID   A0AAU8IQ78
Organism   Streptomyces sp. HUAS MG91     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1907157..1917798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABII15_RS08785 (ABII15_08785) - 1907297..1907803 (+) 507 WP_353941711.1 HNH endonuclease -
  ABII15_RS08790 (ABII15_08790) - 1907915..1908838 (-) 924 WP_353941712.1 SPFH domain-containing protein -
  ABII15_RS08795 (ABII15_08795) - 1908976..1909410 (-) 435 WP_353941713.1 NfeD family protein -
  ABII15_RS08800 (ABII15_08800) - 1909481..1910278 (-) 798 WP_353941714.1 ABC transporter ATP-binding protein -
  ABII15_RS08805 (ABII15_08805) - 1910454..1911236 (+) 783 WP_353941715.1 hypothetical protein -
  ABII15_RS08810 (ABII15_08810) - 1911320..1911559 (-) 240 WP_353941716.1 chaplin -
  ABII15_RS08815 (ABII15_08815) - 1911728..1911973 (-) 246 WP_353941717.1 chaplin -
  ABII15_RS08820 (ABII15_08820) vraR 1912157..1912798 (-) 642 WP_353941718.1 response regulator transcription factor Regulator
  ABII15_RS08825 (ABII15_08825) - 1912791..1913936 (-) 1146 WP_353941719.1 GAF domain-containing sensor histidine kinase -
  ABII15_RS08830 (ABII15_08830) - 1914127..1914825 (+) 699 WP_353941720.1 SDR family oxidoreductase -
  ABII15_RS08835 (ABII15_08835) - 1914822..1915904 (+) 1083 WP_353941721.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  ABII15_RS08840 (ABII15_08840) - 1916224..1916964 (+) 741 WP_353941722.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22783.07 Da        Isoelectric Point: 5.1498

>NTDB_id=912690 ABII15_RS08820 WP_353941718.1 1912157..1912798(-) (vraR) [Streptomyces sp. HUAS MG91]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELRPDVVLMDVKMPGMDGVEALRTLRELANPAK
VLIVTSFTEQRTVIPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEETTGGQGRGGSLTEREREVL
GLIADGRSNREIARALILSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=912690 ABII15_RS08820 WP_353941718.1 1912157..1912798(-) (vraR) [Streptomyces sp. HUAS MG91]
GTGGCTGACGCGATCAAGGTCCTGCTGGTCGACGACCACCAGGTCGTCCGCCGCGGCCTGCGCACGTTCCTGGAGGTCCA
GGACGACATCGAGGTCGTCGGCGAGGCGGCCGACGGCGCGGAGGGAGTCGCCCGCGCCGAGGAGCTCCGGCCCGACGTCG
TGCTCATGGACGTCAAGATGCCCGGCATGGACGGCGTCGAGGCCCTGCGCACACTGCGCGAACTGGCCAACCCGGCCAAG
GTCCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTGATCCCCGCGCTGCGCGCCGGAGCCGCCGGTTACGTGTACAA
GGACGTGGATCCCGACGCCCTGGCCGGCGCCATCCGCTCCGTCCACGCGGGCCACATCCTGCTCCAGCCGGAGGTGGCGG
GCGCCCTGCTCTCCCAGGAGGAGACCACCGGCGGGCAGGGCAGAGGCGGTTCCCTCACCGAGCGGGAGCGGGAGGTGCTC
GGCCTGATCGCCGACGGCCGCTCGAACCGGGAGATCGCCCGCGCCCTGATCCTCTCCGAGAAGACCGTCAAGACCCACGT
GTCGAACATCCTCATGAAACTCGACCTCGCGGACCGCACCCAGGCCGCGCTCTGGGCCGTACGCCACGGAGCGGCGGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AAU8IQ78

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.86

97.183

0.455
  degU Bacillus subtilis subsp. subtilis str. 168

39.367

100

0.408