Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   U0N78_RS06500 Genome accession   NZ_CP140109
Coordinates   1319820..1321046 (-) Length   408 a.a.
NCBI ID   WP_024411303.1    Uniprot ID   A0A4V6U7H0
Organism   Streptococcus suis strain 2022WUSS148     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1314820..1326046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS06475 (U0N78_06475) - 1315562..1316137 (-) 576 WP_044781366.1 thymidine kinase -
  U0N78_RS06480 (U0N78_06480) - 1316583..1316765 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  U0N78_RS06485 (U0N78_06485) lepA 1316815..1318647 (-) 1833 WP_256768933.1 translation elongation factor 4 -
  U0N78_RS06490 (U0N78_06490) ndk 1318743..1319156 (-) 414 WP_105134241.1 nucleoside-diphosphate kinase -
  U0N78_RS06495 (U0N78_06495) yihA 1319179..1319766 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  U0N78_RS06500 (U0N78_06500) clpX 1319820..1321046 (-) 1227 WP_024411303.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  U0N78_RS06505 (U0N78_06505) - 1321244..1321756 (-) 513 WP_105140179.1 dihydrofolate reductase -
  U0N78_RS06510 (U0N78_06510) - 1321931..1322770 (-) 840 WP_105095072.1 thymidylate synthase -
  U0N78_RS06515 (U0N78_06515) - 1322822..1323124 (-) 303 WP_105095073.1 hypothetical protein -
  U0N78_RS06520 (U0N78_06520) - 1323136..1323414 (-) 279 WP_024416195.1 hypothetical protein -
  U0N78_RS06525 (U0N78_06525) - 1323539..1324498 (-) 960 WP_174850184.1 ROK family glucokinase -
  U0N78_RS06530 (U0N78_06530) - 1324593..1324928 (-) 336 WP_174850183.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45319.82 Da        Isoelectric Point: 4.6047

>NTDB_id=912588 U0N78_RS06500 WP_024411303.1 1319820..1321046(-) (clpX) [Streptococcus suis strain 2022WUSS148]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLDILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=912588 U0N78_RS06500 WP_024411303.1 1319820..1321046(-) (clpX) [Streptococcus suis strain 2022WUSS148]
ATGGCTGTTAAGCATACCCATGAGTTGATTTATTGCTCATTTTGTGGAAAAAATCAAGAAGAAGTTAAAAAAATTATTGC
AGGAAACAATGTTTTCATTTGTAATGAGTGTGTGGAGTTAGCTCAAGAAATCATTCGTGAAGAACTAGCAGAAGAAGTGT
TGACAGACTTGGCTGACACACCTAAGCCACAGGAATTGCTCGATATTTTAAACAATTATGTCATTGGACAAGATCGTGCT
AAACGTGCATTGGCTGTCGCTGTCTACAACCATTACAAACGTATCAATTTCCAAGATAGTCGCGATGAAAATGATGTTGA
TTTACAGAAATCAAACATTCTCATGATTGGTCCAACAGGTTCTGGTAAGACATTCTTGGCTCAAACCTTGGCTAAAAGTC
TGAATGTTCCATTTGCCATTGCGGATGCGACCGCTCTTACTGAAGCTGGTTATGTTGGTGAAGATGTCGAAAACATCCTT
CTCAAACTCTTGCAGGCGGCGGATTTTAACATCGATCGTGCTGAAAGAGGGATTATCTATGTGGATGAAATTGATAAGAT
TGCCAAAAAAGGTGAAAATGTGTCTATTACCCGCGATGTTTCGGGTGAAGGTGTCCAACAGGCTCTCTTGAAAATCATCG
AGGGAACAGTTGCCAGCGTTCCACCGCAAGGCGGACGCAAGCATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTATTCATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACGGAACCAAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGGCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V6U7H0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574