Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   L6419_RS06095 Genome accession   NZ_AP025332
Coordinates   1263090..1263827 (-) Length   245 a.a.
NCBI ID   WP_155997673.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1258090..1268827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS06065 (GUT184_11560) - 1258847..1259479 (+) 633 WP_237374453.1 ABC transporter ATP-binding protein -
  L6419_RS06070 (GUT184_11570) - 1260267..1260578 (-) 312 WP_162496986.1 bacteriocin immunity protein -
  L6419_RS06075 (GUT184_11580) - 1260578..1260811 (-) 234 WP_237375177.1 bacteriocin -
  L6419_RS06080 (GUT184_11590) - 1261033..1261263 (-) 231 WP_237375180.1 bacteriocin class II family protein -
  L6419_RS06085 (GUT184_11600) - 1261554..1261679 (+) 126 WP_079276156.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  L6419_RS06090 (GUT184_11610) - 1261736..1263076 (-) 1341 WP_156009378.1 sensor histidine kinase -
  L6419_RS06095 (GUT184_11620) comE/blpR 1263090..1263827 (-) 738 WP_155997673.1 response regulator transcription factor Regulator
  L6419_RS10110 - 1263858..1264019 (-) 162 WP_079276155.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  L6419_RS06100 (GUT184_11640) nt5e 1265089..1267158 (-) 2070 WP_237375181.1 cell surface ecto-5'-nucleotidase Nt5e -
  L6419_RS06105 (GUT184_11650) - 1267291..1268559 (-) 1269 WP_155970560.1 dihydroorotase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28576.13 Da        Isoelectric Point: 7.1059

>NTDB_id=91188 L6419_RS06095 WP_155997673.1 1263090..1263827(-) (comE/blpR) [Streptococcus ruminantium strain GUT-184]
MNIFVLEDDIIQQTRIEKVLNNLLEKHKIEPKKLIISGKPEQLIASVEEKGTHQLFFLDIEIRSEELKGLKVAKQIRDID
PYAIIIFVTTHSEFMPLSFRYQVSALDYIEKELATKEFESRIETALLYAVSKDSKTVAEDSFYFKSKYAQVQYPFDEVYY
VETSPRPHRVILYTRTDCMEFTASLLDILKQEKRLVQCHRSFLINPANVIKIDRQAKVVYFPNGTHCLVARKKLDVTLAT
IDQLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=91188 L6419_RS06095 WP_155997673.1 1263090..1263827(-) (comE/blpR) [Streptococcus ruminantium strain GUT-184]
ATGAATATATTTGTACTAGAAGATGATATTATACAACAAACAAGGATTGAAAAAGTGCTTAACAATCTTTTGGAGAAACA
TAAAATAGAGCCCAAAAAACTTATTATTTCTGGGAAACCCGAACAGTTGATTGCTTCAGTGGAGGAGAAAGGGACGCACC
AGTTGTTCTTTTTGGATATTGAGATAAGATCAGAAGAACTTAAAGGTCTTAAAGTCGCTAAACAAATCAGAGATATTGAT
CCTTATGCTATTATTATTTTTGTGACGACGCATTCTGAATTTATGCCTCTCTCTTTTCGTTATCAAGTATCAGCATTAGA
TTATATTGAAAAGGAACTAGCAACGAAAGAATTTGAATCTCGCATAGAAACAGCTTTACTGTATGCAGTGAGTAAAGATA
GTAAAACAGTAGCTGAGGATTCTTTCTATTTCAAATCTAAATATGCCCAAGTTCAGTACCCATTTGATGAAGTTTACTAT
GTTGAAACGTCTCCAAGACCACATAGGGTTATCCTTTATACAAGAACTGATTGTATGGAGTTCACCGCCAGTTTATTAGA
TATTTTAAAGCAAGAAAAGAGACTGGTACAGTGTCATCGTTCGTTTCTTATCAATCCTGCAAATGTTATCAAAATAGATA
GACAAGCCAAAGTTGTTTATTTTCCCAATGGGACACATTGTTTGGTTGCAAGAAAAAAATTAGATGTTACTTTGGCGACT
ATAGACCAGTTGCACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.066

98.776

0.514
  comE/comE1 Streptococcus equinus JB1

41.423

97.551

0.404

Multiple sequence alignment