Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   L6419_RS03035 Genome accession   NZ_AP025332
Coordinates   601628..602317 (+) Length   229 a.a.
NCBI ID   WP_024532842.1    Uniprot ID   A0A2Z5TS70
Organism   Streptococcus ruminantium strain GUT-184     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 596628..607317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS03015 (GUT184_05460) - 597765..597989 (+) 225 WP_120172055.1 DUF4059 family protein -
  L6419_RS03020 (GUT184_05470) trxB 598003..598920 (+) 918 WP_120172054.1 thioredoxin-disulfide reductase -
  L6419_RS03025 (GUT184_05480) - 598930..599478 (+) 549 WP_237375641.1 YceD family protein -
  L6419_RS03030 (GUT184_05490) gndA 599769..601196 (+) 1428 WP_024532843.1 NADP-dependent phosphogluconate dehydrogenase -
  L6419_RS03035 (GUT184_05500) covR 601628..602317 (+) 690 WP_024532842.1 response regulator transcription factor Regulator
  L6419_RS03040 (GUT184_05510) - 602784..603914 (+) 1131 WP_024532841.1 AI-2E family transporter -
  L6419_RS03045 (GUT184_05520) nrdR 603987..604460 (+) 474 WP_156018319.1 transcriptional regulator NrdR -
  L6419_RS03050 (GUT184_05530) - 604465..605613 (+) 1149 WP_155964995.1 replication initiation/membrane attachment protein -
  L6419_RS03055 (GUT184_05540) dnaI 605613..606512 (+) 900 WP_155964251.1 primosomal protein DnaI -
  L6419_RS03060 (GUT184_05550) - 606509..607222 (+) 714 WP_162496992.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26184.11 Da        Isoelectric Point: 5.9622

>NTDB_id=91180 L6419_RS03035 WP_024532842.1 601628..602317(+) (covR) [Streptococcus ruminantium strain GUT-184]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYVSTGKEALSLAHETDFDLILMSFQLSDMSSKELAKELLAMKPATVMIVA
MDPADVSQHGEEVLAYAVSYVVKPFVISDLVEQISAIFRGRDFIDNHCKQVHLHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEAVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPNQESYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=91180 L6419_RS03035 WP_024532842.1 601628..602317(+) (covR) [Streptococcus ruminantium strain GUT-184]
ATGGCTAAGAAAATTTTGATTGCTGGAAAAGAGCGCAATCTATCGCATTTTGTTTCTATGGAATTGCAAAAAAAGGATTA
CCTTGTGGACTATGTGTCAACCGGAAAGGAAGCCCTGTCTTTGGCTCATGAAACAGATTTTGACTTAATTCTGATGAGTT
TTCAGCTATCAGATATGTCTAGTAAGGAATTAGCCAAGGAGTTACTGGCAATGAAGCCTGCAACGGTCATGATTGTAGCA
ATGGATCCTGCGGATGTGTCCCAGCATGGCGAGGAAGTATTGGCCTATGCTGTATCCTATGTGGTGAAACCTTTTGTTAT
CAGTGACTTGGTGGAGCAAATTTCCGCTATTTTTCGTGGTCGAGACTTTATTGATAATCACTGCAAGCAGGTTCATTTGC
ACGCTGCTTATCGGGATTTAAAGGTTGATTTTCAAAATCGAACGGTAACGCGTGGGGATGAGTTAATCAATCTAACCCGC
CGTGAATACGATTTACTAGCAACCTTGATGAATAGTCCTGAAGCGGTCAGTCGGGAGCAGCTCTTAGAGCGAGTTTGGAA
ATATGAAGCTGCCTCTGAAACGAATGTAGTAGATGTTTATATTCGTTATTTACGAGGGAAATTAGACTTACCCAATCAGG
AGTCTTATATCAAAACAGTTCGCGGTGTCGGCTATGCCATGCGTGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TS70

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.305

100

0.498
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.913

100

0.441

Multiple sequence alignment