Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABVR74_RS07685 Genome accession   NZ_CP159484
Coordinates   1546868..1547497 (-) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis subsp. lactis strain CBA3648     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1541868..1552497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABVR74_RS07660 (ABVR74_07660) - 1542797..1544041 (-) 1245 WP_058223110.1 FtsW/RodA/SpoVE family cell cycle protein -
  ABVR74_RS07665 (ABVR74_07665) - 1544263..1544868 (-) 606 WP_012897545.1 TVP38/TMEM64 family protein -
  ABVR74_RS07670 (ABVR74_07670) - 1544865..1545296 (-) 432 WP_003131405.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  ABVR74_RS07675 (ABVR74_07675) - 1545298..1545888 (-) 591 WP_012897543.1 peptidylprolyl isomerase -
  ABVR74_RS07680 (ABVR74_07680) - 1545991..1546797 (-) 807 WP_058223111.1 Cof-type HAD-IIB family hydrolase -
  ABVR74_RS07685 (ABVR74_07685) vraR 1546868..1547497 (-) 630 WP_003131402.1 response regulator transcription factor Regulator
  ABVR74_RS07690 (ABVR74_07690) - 1547525..1548523 (-) 999 WP_012897540.1 sensor histidine kinase -
  ABVR74_RS07695 (ABVR74_07695) liaF 1548520..1549149 (-) 630 WP_003131399.1 cell wall-active antibiotics response protein LiaF -
  ABVR74_RS07700 (ABVR74_07700) rpsN 1549316..1549585 (-) 270 WP_010905608.1 30S ribosomal protein S14 -
  ABVR74_RS07705 (ABVR74_07705) - 1549683..1550981 (-) 1299 WP_058223112.1 LCP family protein -
  ABVR74_RS07710 (ABVR74_07710) - 1551012..1552211 (-) 1200 WP_058208370.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=911669 ABVR74_RS07685 WP_003131402.1 1546868..1547497(-) (vraR) [Lactococcus lactis subsp. lactis strain CBA3648]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=911669 ABVR74_RS07685 WP_003131402.1 1546868..1547497(-) (vraR) [Lactococcus lactis subsp. lactis strain CBA3648]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACGCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCAGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATCGCATCTGCGATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416