Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   U0450_RS10325 Genome accession   NZ_CP139863
Coordinates   1995203..1996012 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain 15P2112     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1990203..2001012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS10310 mutY 1991925..1993100 (+) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  U0450_RS10315 micA 1993155..1993859 (+) 705 WP_000722076.1 response regulator YycF Regulator
  U0450_RS10320 micB 1993852..1995201 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  U0450_RS10325 vicX 1995203..1996012 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  U0450_RS10330 relB 1996103..1996345 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  U0450_RS10335 - 1996347..1996601 (+) 255 WP_001823540.1 type II toxin-antitoxin system RelE/ParE family toxin -
  U0450_RS10340 - 1996648..1997421 (+) 774 WP_000725951.1 potassium channel family protein -
  U0450_RS10345 - 1997684..1998670 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=911608 U0450_RS10325 WP_001289493.1 1995203..1996012(+) (vicX) [Streptococcus pneumoniae strain 15P2112]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=911608 U0450_RS10325 WP_001289493.1 1995203..1996012(+) (vicX) [Streptococcus pneumoniae strain 15P2112]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAATAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773