Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   U0450_RS03520 Genome accession   NZ_CP139863
Coordinates   701758..702447 (-) Length   229 a.a.
NCBI ID   WP_000518010.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P2112     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 696758..707447
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS03495 - 697493..697822 (-) 330 WP_000196977.1 transposase -
  U0450_RS03500 - 698485..698823 (+) 339 Protein_695 lantibiotic-modifying protein -
  U0450_RS03505 - 698723..699310 (+) 588 WP_001835194.1 lanthionine synthetase LanC family protein -
  U0450_RS03510 - 699353..700585 (+) 1233 WP_000765674.1 MFS transporter -
  U0450_RS03515 cbpC 700704..701660 (-) 957 WP_127244989.1 choline-binding protein CbpC -
  U0450_RS03520 covR 701758..702447 (-) 690 WP_000518010.1 response regulator transcription factor Regulator
  U0450_RS03525 gndA 702459..703883 (-) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  U0450_RS03530 mapZ 703959..705353 (-) 1395 WP_000039284.1 mid-cell-anchored protein MapZ -
  U0450_RS03535 - 705366..706523 (-) 1158 WP_322396531.1 class I SAM-dependent RNA methyltransferase -
  U0450_RS03545 gpsB 707009..707338 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26862.16 Da        Isoelectric Point: 6.9836

>NTDB_id=911547 U0450_RS03520 WP_000518010.1 701758..702447(-) (covR) [Streptococcus pneumoniae strain 15P2112]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=911547 U0450_RS03520 WP_000518010.1 701758..702447(-) (covR) [Streptococcus pneumoniae strain 15P2112]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTACAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463