Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   U0449_RS06730 Genome accession   NZ_CP139862
Coordinates   1326629..1327249 (+) Length   206 a.a.
NCBI ID   WP_000839909.1    Uniprot ID   A0A098Z2X2
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1321629..1332249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS06705 - 1321663..1322295 (-) 633 WP_000571422.1 ABC transporter ATP-binding protein -
  U0449_RS06710 - 1322297..1324312 (-) 2016 WP_000732372.1 DUF1430 domain-containing protein -
  U0449_RS06715 - 1324415..1324711 (-) 297 WP_000911560.1 lactococcin 972 family bacteriocin -
  U0449_RS06720 - 1325026..1325195 (-) 170 Protein_1299 PhrA family quorum-sensing system peptide -
  U0449_RS06725 - 1325383..1326246 (+) 864 WP_001093627.1 helix-turn-helix domain-containing protein -
  U0449_RS06730 comM 1326629..1327249 (+) 621 WP_000839909.1 hypothetical protein Regulator
  U0449_RS06735 tsaE 1327335..1327778 (+) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  U0449_RS06740 - 1327768..1328286 (+) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  U0449_RS06745 brpA 1328294..1329310 (+) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  U0449_RS06750 cinA 1329395..1330651 (+) 1257 WP_000642704.1 competence/damage-inducible protein A Machinery gene
  U0449_RS06755 recA 1330706..1331872 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23540.66 Da        Isoelectric Point: 10.1254

>NTDB_id=911505 U0449_RS06730 WP_000839909.1 1326629..1327249(+) (comM) [Streptococcus pneumoniae strain 05H0020-2]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=911505 U0449_RS06730 WP_000839909.1 1326629..1327249(+) (comM) [Streptococcus pneumoniae strain 05H0020-2]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z2X2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364
  comM Streptococcus mitis SK321

38.462

94.66

0.364