Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   U0449_RS03460 Genome accession   NZ_CP139862
Coordinates   684129..684818 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 679129..689818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS03430 - 679864..679986 (-) 123 Protein_683 hypothetical protein -
  U0449_RS03435 - 680026..680193 (-) 168 Protein_684 transposase -
  U0449_RS03440 - 680856..681194 (+) 339 Protein_685 lantibiotic-modifying protein -
  U0449_RS03445 - 681094..681681 (+) 588 WP_001835194.1 lanthionine synthetase LanC family protein -
  U0449_RS03450 - 681724..682956 (+) 1233 WP_000765674.1 MFS transporter -
  U0449_RS03455 cbpC 683075..684031 (-) 957 WP_050218855.1 choline-binding protein CbpC -
  U0449_RS03460 covR 684129..684818 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  U0449_RS03465 gndA 684830..686254 (-) 1425 WP_050218856.1 NADP-dependent phosphogluconate dehydrogenase -
  U0449_RS03470 mapZ 686330..687724 (-) 1395 WP_000039273.1 mid-cell-anchored protein MapZ -
  U0449_RS03475 - 687737..688894 (-) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  U0449_RS03485 gpsB 689380..689709 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=911470 U0449_RS03460 WP_000518011.1 684129..684818(-) (covR) [Streptococcus pneumoniae strain 05H0020-2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=911470 U0449_RS03460 WP_000518011.1 684129..684818(-) (covR) [Streptococcus pneumoniae strain 05H0020-2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467