Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   U0447_RS09980 Genome accession   NZ_CP139861
Coordinates   1923997..1925799 (+) Length   600 a.a.
NCBI ID   WP_081528464.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1918997..1930799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS09960 rnr 1919292..1921646 (+) 2355 WP_288165833.1 ribonuclease R -
  U0447_RS09965 smpB 1921609..1922076 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  U0447_RS09970 tehB 1922092..1922952 (+) 861 WP_000413763.1 SAM-dependent methyltransferase TehB -
  U0447_RS09975 coiA 1923025..1923978 (+) 954 WP_288165834.1 competence protein CoiA Machinery gene
  U0447_RS09980 pepF 1923997..1925799 (+) 1803 WP_081528464.1 oligoendopeptidase F Regulator
  U0447_RS09985 - 1925801..1926514 (+) 714 WP_000230399.1 O-methyltransferase -
  U0447_RS09990 prsA 1926581..1927522 (+) 942 WP_081528463.1 peptidylprolyl isomerase PrsA -
  U0447_RS09995 - 1927641..1927982 (-) 342 Protein_1922 transposase -
  U0447_RS10000 - 1928397..1928492 (+) 96 Protein_1923 IS630 family transposase -
  U0447_RS10005 - 1928745..1929365 (-) 621 WP_000780813.1 histidine phosphatase family protein -
  U0447_RS10010 - 1929365..1929847 (-) 483 WP_050115304.1 aminoacyl-tRNA deacylase -
  U0447_RS10015 - 1929847..1930689 (-) 843 WP_000954122.1 DUF368 domain-containing protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69925.81 Da        Isoelectric Point: 4.5274

>NTDB_id=911453 U0447_RS09980 WP_081528464.1 1923997..1925799(+) (pepF) [Streptococcus pneumoniae strain 16H2017-2]
MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALEANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=911453 U0447_RS09980 WP_081528464.1 1923997..1925799(+) (pepF) [Streptococcus pneumoniae strain 16H2017-2]
ATGGTATTACAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTGCGGATAACC
TACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATGGAGAAGCTTTACGTTTATGCTCATATGAAGAATGAC
CAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCAAGCCTTTTC
ATTCTATGATCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGCTGCAGGTTT
ATCAACACTATTTTGACAAGCTCTTGCAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTGGCTGGAGCT
GGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGTCCTAGACGA
TGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTCGCCGTGGTG
CCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTTAAGGTGCAA
AATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGAAGCGAATTTTGTTCCAGAAAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAATCTTGGGGA
TTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAGTTTTACCTACCAAGAAGCCTTGAAA
AAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTCAAACGTGCCTTCAGCGAGCGTTGGATTGA
TGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTATGATACCAATGCCTTTATGCTTCTCAACT
GGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACTCGTGAAACT
CAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTGGAACAGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACAAGCGATTTC
CTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCTCGTATTCCACACTTTTACTATAACTACTATGTATATCAATATTCAACTGGATTTGCGGCCGCCTCAGCCTTGGCTG
AAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGACTATCCACTT
AATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGAACGCCGTTT
AAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.114

99.333

0.667