Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   U0447_RS07315 Genome accession   NZ_CP139861
Coordinates   1395061..1395750 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1390061..1400750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS07290 gpsB 1390170..1390499 (+) 330 WP_000146522.1 cell division regulator GpsB -
  U0447_RS07300 - 1390985..1392142 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  U0447_RS07305 mapZ 1392155..1393549 (+) 1395 WP_000039310.1 mid-cell-anchored protein MapZ -
  U0447_RS07310 gndA 1393625..1395049 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  U0447_RS07315 covR 1395061..1395750 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  U0447_RS07320 cbpC 1395848..1396873 (+) 1026 WP_000698031.1 choline-binding protein CbpC -
  U0447_RS07325 - 1396892..1397767 (+) 876 WP_000771137.1 choline-binding protein CbpJ -
  U0447_RS07330 - 1397885..1399117 (-) 1233 WP_000765668.1 MFS transporter -
  U0447_RS07335 - 1399160..1400035 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=911438 U0447_RS07315 WP_000518011.1 1395061..1395750(+) (covR) [Streptococcus pneumoniae strain 16H2017-2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=911438 U0447_RS07315 WP_000518011.1 1395061..1395750(+) (covR) [Streptococcus pneumoniae strain 16H2017-2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467