Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   U0447_RS04430 Genome accession   NZ_CP139861
Coordinates   830295..831248 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 825295..836248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS04400 - 826056..826679 (-) 624 WP_000932632.1 hypothetical protein -
  U0447_RS04405 jag 826730..827716 (-) 987 WP_000260011.1 RNA-binding cell elongation regulator Jag/EloR -
  U0447_RS04410 - 827735..828559 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  U0447_RS04415 rnpA 828534..828905 (-) 372 WP_000739246.1 ribonuclease P protein component -
  U0447_RS04420 - 828922..829053 (-) 132 WP_000768904.1 hypothetical protein -
  U0447_RS04425 - 829054..830244 (-) 1191 WP_000167753.1 acetate kinase -
  U0447_RS04430 comYH 830295..831248 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  U0447_RS04435 - 831309..831903 (-) 595 Protein_840 class I SAM-dependent methyltransferase -
  U0447_RS04440 comGG/cglG 832040..832453 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  U0447_RS04445 comGF/cglF 832431..832892 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  U0447_RS04450 comGE/cglE 832855..833157 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  U0447_RS04455 comGD/cglD 833120..833524 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  U0447_RS04460 comGC/cglC 833517..833843 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  U0447_RS04465 comGB/cglB 833845..834861 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  U0447_RS04470 comGA/cglA/cilD 834809..835750 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  U0447_RS04475 - 835826..836191 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=911409 U0447_RS04430 WP_000345126.1 830295..831248(-) (comYH) [Streptococcus pneumoniae strain 16H2017-2]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=911409 U0447_RS04430 WP_000345126.1 830295..831248(-) (comYH) [Streptococcus pneumoniae strain 16H2017-2]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAACCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536