Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   U0447_RS03905 Genome accession   NZ_CP139861
Coordinates   736747..737367 (-) Length   206 a.a.
NCBI ID   WP_000839909.1    Uniprot ID   A0A098Z2X2
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 731747..742367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS03880 recA 732124..733290 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  U0447_RS03885 cinA 733345..734601 (-) 1257 WP_000642704.1 competence/damage-inducible protein A Machinery gene
  U0447_RS03890 brpA 734686..735702 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  U0447_RS03895 - 735710..736228 (-) 519 WP_050232568.1 GNAT family N-acetyltransferase -
  U0447_RS03900 tsaE 736218..736661 (-) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  U0447_RS03905 comM 736747..737367 (-) 621 WP_000839909.1 hypothetical protein Regulator
  U0447_RS03910 - 737750..738613 (-) 864 WP_050232569.1 helix-turn-helix domain-containing protein -
  U0447_RS03915 - 738807..738959 (+) 153 WP_152411221.1 PhrA family quorum-sensing system peptide -
  U0447_RS03920 - 739274..739570 (+) 297 WP_000911559.1 lactococcin 972 family bacteriocin -
  U0447_RS03925 - 739673..741688 (+) 2016 WP_000732381.1 bacteriocin-associated integral membrane family protein -
  U0447_RS03930 - 741690..742322 (+) 633 WP_000571419.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23540.66 Da        Isoelectric Point: 10.1254

>NTDB_id=911403 U0447_RS03905 WP_000839909.1 736747..737367(-) (comM) [Streptococcus pneumoniae strain 16H2017-2]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=911403 U0447_RS03905 WP_000839909.1 736747..737367(-) (comM) [Streptococcus pneumoniae strain 16H2017-2]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z2X2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364
  comM Streptococcus mitis SK321

38.462

94.66

0.364