Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SUT_RS04730 Genome accession   NZ_AP025331
Coordinates   980135..980872 (+) Length   245 a.a.
NCBI ID   WP_155970879.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-183     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 975135..985872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUT_RS04720 (GUT183_08940) - 975355..976623 (+) 1269 WP_155996447.1 dihydroorotase -
  SUT_RS04725 (GUT183_08950) nt5e 976756..978825 (+) 2070 WP_237373633.1 cell surface ecto-5'-nucleotidase Nt5e -
  SUT_RS10350 - 979943..980104 (+) 162 WP_155963077.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  SUT_RS04730 (GUT183_08970) comE/blpR 980135..980872 (+) 738 WP_155970879.1 response regulator transcription factor Regulator
  SUT_RS04735 (GUT183_08980) - 980886..982226 (+) 1341 WP_237373634.1 sensor histidine kinase -
  SUT_RS04740 (GUT183_08990) - 982283..982408 (-) 126 WP_079276156.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SUT_RS04745 (GUT183_09000) - 982699..982932 (+) 234 WP_024532803.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SUT_RS04750 (GUT183_09010) - 982932..983243 (+) 312 WP_165437883.1 bacteriocin immunity protein -
  SUT_RS04755 (GUT183_09030) - 984033..984665 (-) 633 WP_120171642.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28506.00 Da        Isoelectric Point: 7.1059

>NTDB_id=91139 SUT_RS04730 WP_155970879.1 980135..980872(+) (comE/blpR) [Streptococcus ruminantium strain GUT-183]
MNIFVLEDDIIQQTRIEKVLNNLLEKHKIEPKKLIISGKPEQLIASVEEKGAHQLFFLDIEIRSEELKGLKVAKQIRDID
PYAIIIFVTTHSEFMPLSFRYQVSALDYIEKELATKEFESRIETALLYAVSKDSKTVAEDSFYFKSKYAQVQYPFDEVYY
VETSPRPHRVILYTRTDCMEFTASLSDVLKQEKRLVQCHRSFLINPANVIKIDRQAKVVYFPNGTHCLVARKKLDVTLAT
IDQLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=91139 SUT_RS04730 WP_155970879.1 980135..980872(+) (comE/blpR) [Streptococcus ruminantium strain GUT-183]
ATGAATATATTTGTACTAGAAGATGATATTATACAACAAACAAGGATTGAAAAAGTGCTTAACAATCTTTTGGAGAAACA
TAAAATAGAGCCCAAAAAACTTATTATTTCTGGGAAACCCGAACAGTTGATTGCTTCAGTGGAGGAGAAAGGGGCGCACC
AGTTGTTCTTTTTGGATATTGAGATAAGATCAGAAGAACTTAAAGGTCTTAAAGTCGCTAAACAAATCAGAGATATTGAT
CCTTATGCTATTATTATTTTTGTGACGACGCATTCTGAATTTATGCCTCTCTCTTTTCGTTATCAAGTATCAGCATTAGA
TTATATTGAAAAGGAACTAGCAACGAAAGAATTTGAATCTCGCATAGAAACAGCTTTACTGTATGCAGTGAGTAAAGATA
GTAAAACAGTAGCTGAGGATTCTTTCTATTTCAAATCTAAATATGCCCAAGTTCAGTACCCATTTGATGAAGTTTATTAT
GTTGAAACGTCTCCAAGACCACATAGGGTTATCCTTTATACAAGAACTGATTGTATGGAGTTTACCGCCAGTTTATCAGA
TGTTTTAAAGCAAGAAAAGAGACTGGTACAGTGTCATCGTTCGTTTCTTATCAATCCTGCGAATGTTATCAAAATAGATA
GACAAGCCAAAGTTGTTTATTTTCCCAATGGGACACATTGTTTGGTTGCAAGAAAAAAATTAGATGTTACTTTGGCGACT
ATAGACCAGTTGCACTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-234)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

51.653

98.776

0.51
  comE/comE1 Streptococcus equinus JB1

41.841

97.551

0.408

Multiple sequence alignment