Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   U0448_RS07105 Genome accession   NZ_CP139860
Coordinates   1381871..1382560 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain 21011     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1376871..1387560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS07080 gpsB 1376980..1377309 (+) 330 WP_000146522.1 cell division regulator GpsB -
  U0448_RS07090 - 1377795..1378952 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  U0448_RS07095 mapZ 1378965..1380359 (+) 1395 WP_050258733.1 mid-cell-anchored protein MapZ -
  U0448_RS07100 gndA 1380435..1381859 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  U0448_RS07105 covR 1381871..1382560 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  U0448_RS07110 cbpC 1382659..1383681 (+) 1023 WP_050258732.1 choline-binding protein CbpC -
  U0448_RS07115 cbpJ 1383700..1384698 (+) 999 WP_044727649.1 choline-binding protein CbpJ -
  U0448_RS07120 - 1384721..1385974 (-) 1254 WP_081570892.1 MFS transporter -
  U0448_RS07125 - 1385985..1386893 (-) 909 WP_257899049.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=911360 U0448_RS07105 WP_000518008.1 1381871..1382560(+) (covR) [Streptococcus pneumoniae strain 21011]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=911360 U0448_RS07105 WP_000518008.1 1381871..1382560(+) (covR) [Streptococcus pneumoniae strain 21011]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCACGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467