Detailed information NTG0911328

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: U0448_RS04025
• Genome accession: NZ_CP139860
• Coordinates: 795210..796220 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 21011
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 790210..801220

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0448_RS04000	-	791420..791713 (-)	294	WP_000977365.1	hypothetical protein	-
U0448_RS04005	-	791875..792327 (+)	453	WP_081570997.1	universal stress protein	-
U0448_RS04010	-	792362..793750 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
U0448_RS04015	-	793816..794778 (+)	963	WP_081570996.1	asparaginase	-
U0448_RS04020	-	794775..795146 (-)	372	WP_219599595.1	hypothetical protein	-
U0448_RS04025	ccpA	795210..796220 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
U0448_RS04030	-	796645..797244 (-)	600	WP_000866729.1	response regulator transcription factor	-
U0448_RS04035	-	797246..798343 (-)	1098	WP_000893550.1	sensor histidine kinase	-
U0448_RS04040	-	798343..799080 (-)	738	WP_000832837.1	ABC transporter permease	-
U0448_RS04045	-	799082..799966 (-)	885	WP_081571030.1	ABC transporter ATP-binding protein	-
U0448_RS04050	-	799953..800147 (-)	195	WP_000820179.1	hypothetical protein	-
U0448_RS04055	-	800144..800350 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=911328 U0448_RS04025 WP_000990607.1 795210..796220(-) (ccpA) [Streptococcus pneumoniae strain 21011]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=911328 U0448_RS04025 WP_000990607.1 795210..796220(-) (ccpA) [Streptococcus pneumoniae strain 21011]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTATCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568