Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SUT_RS02305 Genome accession   NZ_AP025331
Coordinates   448017..449309 (+) Length   430 a.a.
NCBI ID   WP_237373476.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-183     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 443017..454309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUT_RS02275 (GUT183_04230) - 443158..444558 (+) 1401 WP_120171352.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SUT_RS02280 (GUT183_04240) - 444560..444931 (+) 372 WP_024532771.1 S1 RNA-binding domain-containing protein -
  SUT_RS02285 (GUT183_04250) - 445006..445326 (+) 321 WP_155964250.1 transposase -
  SUT_RS02290 (GUT183_04260) - 445323..446207 (+) 885 WP_237373475.1 IS3 family transposase -
  SUT_RS02295 (GUT183_04270) cysK 446309..447235 (-) 927 WP_024533095.1 cysteine synthase A -
  SUT_RS02300 (GUT183_04280) - 447328..447960 (-) 633 WP_156018189.1 YigZ family protein -
  SUT_RS02305 (GUT183_04290) comFA/cflA 448017..449309 (+) 1293 WP_237373476.1 DEAD/DEAH box helicase Machinery gene
  SUT_RS02310 (GUT183_04300) - 449302..449967 (+) 666 WP_156020851.1 ComF family protein -
  SUT_RS02315 (GUT183_04310) hpf 450044..450586 (+) 543 WP_024533091.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 49039.49 Da        Isoelectric Point: 9.3099

>NTDB_id=91126 SUT_RS02305 WP_237373476.1 448017..449309(+) (comFA/cflA) [Streptococcus ruminantium strain GUT-183]
MNELQDYYGRLFTRNQLTAVERERAQTIPSITEKKTCFRCGTSFEEEYQLPNGAFYCRACLLLGRVRSDEKLYYFPQRDF
PRNTCLQWKGRLTNWQQTISDALCANVEKRQATLVHAVTGAGKTEMIYHTVASVIDNGGAVCLASPRIDVCIELYKRLQQ
DFSVPISLLHGESEVYFRTPLVIATTHQLLKFYRAFDLLLIDEVDAFPYADNPVLYRAVDNAVKPDGVQVFLTATSTDQL
EKKIKAGKLERLSLPRRFHGNPLVVPQKIWFSQFEQYLKKGRLTPKLAKAIQHQRKTGYPLLIFVPEISKGMEFTKIVKK
AFPSENIGFVSSQTENRLEIVEGFRNKNITILISTTILERGVTFPCVDVFVIQANHYLYSSSSLVQIAGRVGRSQERPTG
LLHFFHEGSTRAIEKSIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=91126 SUT_RS02305 WP_237373476.1 448017..449309(+) (comFA/cflA) [Streptococcus ruminantium strain GUT-183]
ATGAATGAATTACAAGATTACTATGGAAGACTATTTACCAGGAATCAACTAACAGCAGTTGAGAGAGAAAGAGCGCAGAC
AATTCCAAGTATTACGGAGAAAAAAACTTGTTTCAGATGCGGAACTTCCTTTGAAGAAGAATATCAGTTGCCAAACGGAG
CTTTTTATTGCCGAGCCTGTTTGCTTTTGGGAAGGGTACGCTCGGACGAAAAACTATACTATTTTCCACAGAGAGATTTT
CCTAGAAATACCTGCTTACAGTGGAAAGGACGACTGACCAATTGGCAACAAACCATTTCTGATGCTCTTTGCGCCAATGT
TGAGAAAAGGCAAGCTACGCTGGTCCATGCAGTAACAGGAGCTGGAAAAACAGAGATGATATATCATACAGTGGCTTCCG
TTATTGATAATGGTGGAGCAGTTTGTTTAGCCAGTCCACGAATTGATGTTTGTATCGAACTATATAAGCGCTTACAGCAG
GATTTTTCAGTTCCAATTAGTCTCTTGCACGGAGAATCAGAGGTCTACTTTAGAACCCCCTTGGTTATCGCTACAACTCA
TCAGCTCTTAAAATTTTATCGTGCTTTTGATTTGCTTCTGATTGATGAAGTAGATGCCTTTCCATACGCAGATAATCCTG
TTCTTTATCGGGCAGTAGACAATGCAGTAAAGCCAGATGGTGTACAGGTATTTTTGACAGCTACTTCAACAGATCAACTT
GAGAAAAAGATAAAAGCAGGAAAACTAGAACGCCTTAGTTTACCTAGACGATTTCATGGCAATCCACTAGTAGTACCGCA
AAAAATTTGGTTCAGCCAATTTGAACAGTATCTAAAGAAAGGTAGATTGACCCCTAAGCTGGCAAAAGCTATCCAGCATC
AGCGAAAGACAGGCTATCCCTTGCTAATATTTGTTCCAGAAATCTCAAAAGGGATGGAATTTACAAAGATAGTCAAAAAA
GCATTTCCTAGCGAAAACATTGGTTTTGTTTCCAGTCAGACAGAAAATCGCCTAGAAATAGTAGAAGGATTCCGCAATAA
AAACATCACCATTTTAATCTCAACCACCATTCTTGAACGCGGTGTAACCTTCCCTTGTGTTGATGTCTTTGTTATTCAAG
CCAATCATTATCTCTATAGTTCATCTAGTTTAGTTCAAATAGCAGGTCGAGTTGGTCGCAGCCAAGAACGACCAACAGGG
CTTCTACATTTTTTTCACGAAGGAAGCACGCGGGCGATTGAAAAGTCCATCGCTGAAATCAAACAAATGAATAAGGAGGC
AGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(92-235)

Helicase conserved C-terminal domain (Helicase_C)

(291-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

64.554

99.07

0.64
  comFA/cflA Streptococcus pneumoniae D39

64.554

99.07

0.64
  comFA/cflA Streptococcus pneumoniae R6

64.554

99.07

0.64
  comFA/cflA Streptococcus pneumoniae TIGR4

64.554

99.07

0.64
  comFA/cflA Streptococcus mitis NCTC 12261

63.85

99.07

0.633
  comFA/cflA Streptococcus mitis SK321

63.38

99.07

0.628
  comFA Lactococcus lactis subsp. cremoris KW2

53.652

92.326

0.495
  comFA Latilactobacillus sakei subsp. sakei 23K

38.695

99.767

0.386

Multiple sequence alignment