Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABQ274_RS04285 Genome accession   NZ_CP159281
Coordinates   908410..909039 (-) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis strain FNZ339     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 903410..914039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABQ274_RS04255 (ABQ274_04255) - 903768..904115 (-) 348 Protein_844 alcohol dehydrogenase catalytic domain-containing protein -
  ABQ274_RS04260 (ABQ274_04260) - 904340..905584 (-) 1245 WP_021722277.1 FtsW/RodA/SpoVE family cell cycle protein -
  ABQ274_RS04265 (ABQ274_04265) - 905805..906410 (-) 606 WP_023163942.1 TVP38/TMEM64 family protein -
  ABQ274_RS04270 (ABQ274_04270) - 906407..906838 (-) 432 WP_003131405.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  ABQ274_RS04275 (ABQ274_04275) - 906840..907430 (-) 591 WP_023163941.1 peptidylprolyl isomerase -
  ABQ274_RS04280 (ABQ274_04280) - 907533..908339 (-) 807 WP_003131403.1 Cof-type HAD-IIB family hydrolase -
  ABQ274_RS04285 (ABQ274_04285) vraR 908410..909039 (-) 630 WP_003131402.1 response regulator transcription factor Regulator
  ABQ274_RS04290 (ABQ274_04290) - 909067..910065 (-) 999 WP_012897540.1 sensor histidine kinase -
  ABQ274_RS04295 (ABQ274_04295) liaF 910062..910691 (-) 630 WP_353727560.1 cell wall-active antibiotics response protein LiaF -
  ABQ274_RS04300 (ABQ274_04300) rpsN 910857..911126 (-) 270 WP_010905608.1 30S ribosomal protein S14 -
  ABQ274_RS04305 (ABQ274_04305) - 911229..912527 (-) 1299 WP_023163940.1 LCP family protein -
  ABQ274_RS04310 (ABQ274_04310) - 912558..913714 (-) 1157 Protein_855 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=911155 ABQ274_RS04285 WP_003131402.1 908410..909039(-) (vraR) [Lactococcus lactis strain FNZ339]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=911155 ABQ274_RS04285 WP_003131402.1 908410..909039(-) (vraR) [Lactococcus lactis strain FNZ339]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACTCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCGGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATTGCATCTGCAATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416