Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABU997_RS18275 Genome accession   NZ_CP159152
Coordinates   3465205..3465861 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 10035210-2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3460205..3470861
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABU997_RS18240 (ABU997_18245) dcyD 3461085..3462071 (+) 987 WP_042033531.1 D-cysteine desulfhydrase -
  ABU997_RS18245 (ABU997_18250) tcyL 3462086..3462754 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ABU997_RS18250 (ABU997_18255) tcyN 3462751..3463503 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABU997_RS18255 (ABU997_18260) sdiA 3463733..3464455 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  ABU997_RS18260 (ABU997_18265) yecF 3464522..3464746 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABU997_RS18265 (ABU997_18270) yecU 3464733..3464909 (-) 177 WP_000590344.1 protein YecU -
  ABU997_RS18270 (ABU997_18275) - 3464947..3465063 (-) 117 WP_001302039.1 hypothetical protein -
  ABU997_RS18275 (ABU997_18280) letA 3465205..3465861 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABU997_RS18280 (ABU997_18285) uvrC 3465858..3467690 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ABU997_RS18285 (ABU997_18290) pgsA 3467747..3468295 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABU997_RS18305 (ABU997_18310) yecA 3468945..3469610 (+) 666 WP_042033529.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=911030 ABU997_RS18275 WP_000611328.1 3465205..3465861(+) (letA) [Escherichia coli strain 10035210-2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=911030 ABU997_RS18275 WP_000611328.1 3465205..3465861(+) (letA) [Escherichia coli strain 10035210-2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482